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  • 1975-1979  (2)
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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European archives of oto-rhino-laryngology and head & neck 211 (1975), S. 129-138 
    ISSN: 1434-4726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Im Kopf-Halsbereich stellt die szintigraphische Erfassung maligner Tumoren und deren Metastasen eine gute Bereicherung der diagnostischen Möglichkeiten dar. Zur Untersuchung eignen sich solche Substanzen, die eine hohe Tomoraffinität besitzen und sich gut radioaktiv markieren lassen. Aus diesem Grund wurde für die vorliegenden Untersuchungen das Zytostatikum Bleomycin benutzt und mit57Cobalt markiert. Die szintigraphische Untersuchung erfolgte 4–6 Std nach intravenöser Applikation von 1 mCi57Co-Bleomycin mit Hilfe der Gamma-Kamera. 60 Patienten mit verschiedenen neoplastischen Erkrankungen wurden untersucht, 46 hatten tumoröse Veränderungen im Kopf-Hals-Bereich, die übrigen im Thorax-Abdomen. Von den unbehandelten Kopf-Hals-Malignomen konnten 34 (85%) szintigraphisch nachgewiesen werden; 21 (81%) waren epithelialen und 13 (69%) mesenchymalen Ursprungs. Die Möglichkeiten der Untersuchungsmethode werden dargestellt; ihre klinische Bedeutung besteht im Nachweis von Primärtumoren und deren Metastasen, von Rezidiven und Tumorresten sowie in der Lokalisationsdiagnostik von Fernmetastasen.
    Notes: Summary Tumorscanning of malignomas and their metastatic nodules in head and neck is an enrichment of diagnostic possibilities. For the examination such substances can be used, which are tumoraffine and well to mark with a radio-isotope. Therefore we have marked the cytostatic drug Bleomycine with57Co. Scans were performed with the Anger-Camera 4 to 6 hrs after intravenous injection of 1 mCi57Co-Bleomycine. 60 patients with different malignomas have been examined, 46 with tumor-localization in head and neck, the others in thoraxabdomen. 34 (85%) of the head and neck malignomas could be demonstrated; 21 (81%) were squamous cell carcinomas, 13 (69%) sarcomas. The possibilities of this method are shown; its clinical importance lies in the identification of primary tumors and their metastatic nodules, of relapses and tumorrests as well as the localization of distant metastasises.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European archives of oto-rhino-laryngology and head & neck 210 (1975), S. 268-269 
    ISSN: 1434-4726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The scanning of tumors and their metastasises today means an enrichment of diagnostic possibilities—especially in the head and neck area. So far various radiopharmaceuticals have been used for this examination but the results have only been good with a few of them. We habe marked the cytostatic drug Bleomycine with radioactive 57Co to get a high tumor-specific concentration. On a great number of patients own experiences with the scintigraphic diagnostic for localization using this radiopharmaceutical are reported. Over 85% of the squamous cell carcinomas and over 70% of the sarcomas of head and neck can be demonstrated. The possibilities of this examination, the clinical importance and indication for therapy is shown and discussed on the own cases.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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