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  • 1
    Electronic Resource
    Electronic Resource
    EFFECT OF DELTA-9-TETRAHYDROCANNABINOL ADMINISTRATION ON THE LIPID CONSTITUENTS OF RAT BRAIN SUBCELLULAR FRACTIONS (1975)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 24 (1975), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: An investigation on the effects of acute (10 mg/kg) and chronic (10 mg/kg for 15 days) treatment with Δ9-THC administration by the intraperitoneal route, on the cholesterol, cerebroside and individual phospholipid contents in microsomal, synaptosomal, mitochodrial and myelin fractions from adult rat brain, is reported. The drug has been found to affect the different subcellular membranous lipid and phospholipid components in a characteristic manner.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1975.tb11891.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    EFFECT OF DELTA-9-TETRAHYDROCANNABINOL ON GANGLIOSIDES AND SIALOGLYCOPROTEINS IN SUBCELLULAR FRACTIONS OF RAT BRAIN (1976)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 26 (1976), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: —The present paper reports the result of studies undertaken to determine the effects of the in vivo administration of Δ9-THC on the ganglioside and sialoglycoprotein contents of rat brain subcellular fractions. Results indicate that the administration of the drug under both acute and chronic conditions brings about characteristic changes in the sialoglycoproteins and ganglioside content in all the subcellular fractions. Both sialoglycoproteins and ganglioside contents were markedly increased in microsomal and synaptosomal fractions and decreased in the mitochondrial fractions although the increase in the synaptosomal fractions has been found to be most striking.After chronic treatment, both ganglioside and sialoglycoprotein content did not change substantially in all the fractions except for a small increase in case of synaptosomal fractions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1976.tb04442.x-i1
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Carboxypeptidase activity in developing rat brain (1975)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 25 (1975), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1975.tb04397.x
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Hepatic induction of threonine dehydratase and tryptophan pyrrolase in tyrotoxic rats (1977)
    Springer
    Cellular and molecular life sciences 33 (1977), S. 1018-1019 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The levels of hepatic threonine dehydratase and tryptophan pyrrolase are elevated in 5% tyrosine-fed rats, and these increases are dependent on the dietary tyrosine level. Experiments with RNA and protein synthesis inhibitors indicate that the appearance of these new enzyme activities are dependet on concomitant new protein synthesis and the inducer operates at a transcriptional level.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01945942
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Mescaline-induced changes of brain-cortex ribosomes mescaline demethylase activity of brain-cortex soluble supernatant (1977)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 296 (1977), S. 297-300 
    Details
    ISSN: 1432-1912
    Keywords: Brain-cortex slices ; O-demethylase ; Mescaline ; Soluble supernatant
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Brain-cortex slices demethylate mescaline and p-methoxyacetanilide, a reference O-demethylating substrate, though the rate of demethylation of mescaline is about one third that of the reference substrate. The demethylase activity is localized mostly in the soluble supernatant (105000xg). It is purified 47-fold with respect to the demethylation of mescaline by ammonium sulfate precipitation and DEAE cellulose chromatography. The partially purified demethylase, which is stable for 3–5 days at −5° C in the presence of dithiothreitol and glutathione and is inhibited by p-chloromercuribenzoate, has maximal activity at pH between 7.2 and 8.0. It demethylates mescaline into 3,4-dimethoxy-5-hydroxyphenethylamine and 3,5-dimethoxy-4-hydroxyphenethylamine and some unidentified derivatives.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00498697
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    Paper (German National Licenses)
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