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  • 1
    ISSN: 1432-1459
    Keywords: Cerebellar cortex ; Degeneration of cerebellar cells
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Bei der Autopsie eines 8 Monate alten Kindes, welches infolge einer schweren Gastroenteritis verstarb, fanden sich in der Kleinhirnrinde degenerative Veränderungen mit Befall von Zellen des äußeren Stratum granulare, aber auch der Purkinje- und Golgi II-Zellen. Noch erhaltene Purkinje-Zellen zeigten vakuoläre Veränderungen des Zellkörpers und Anomalien der Dendriten. Zugeordnete Veränderungen fanden sich in den unteren Oliven und in den Moos-Fasern.
    Notes: Summary An 8 month old infant, who died of severe gastroenteritis, presented a degeneration of the cerebellar cortex involving cells arising from the outer granular layer as well as Purkinje and Golgi II cells. Residual Purkinje cells showed vacuolar change of the cell body and dendritic abnormalities. Related lesions were atrophy of the inferior olives and degeneration of the mossy fibers.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1590-3478
    Keywords: Alzheimer's disease ; Creutzfeldt-Jakob ; Transmissible dementias
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Sommario Una grande quantità di neuroni in degenerazione neurofibrillare e di placche senili, fu trovata nella corteccia cerebrale di una donna di 52 anni affetta da una demenza ad evoluzione subacuta, mioclonie e alterazioni elettroencefalografiche periodiche. È questo un caso sporadico di demenza presenile di Alzheimer clinicamente sovrapponibile alla malattia di Creutzfeldt-Jakob, che si presta a ipotizzare un rapporto fra quella malattia e le demenze trasmissibili.
    Notes: Abstract Large numbers of neurofibrillary tangles and neuritic plaques were found in a cerebral biopsy from a 52-year-old woman suffering from subacute dementia with early myoclonus and quasiperiodic EEG changes. This case, which appeared to be an example of non-familial Alzheimer's disease, is commented in the context of possible relation of Alzheimer's disease to transmissible dementia.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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