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  • 1975-1979  (3)
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  • 1
    Electronic Resource
    Electronic Resource
    Characterization of the proteinuria in cadmium-exposed workers (1976)
    Springer
    International archives of occupational and environmental health 38 (1976), S. 19-30 
    Details
    ISSN: 1432-1246
    Keywords: Cadmium ; Proteinuria ; Kidney
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The concentration of several protein (β2-microglobulin, orosomucoid, albumin, transferrin) and of total amino acids was determined in the urine of 18 cadmium-exposed workers and in a group of matched nonexposed workers. The results were compared with the electrophoretic pattern of urinary proteins on agarose gel. Ten of the cadmium-exposed workers had an abnormal electrophoretic pattern, eight of them excreted larger quantities of high and low molecular weight proteins, and the other two showed only an increased excretion of high molecular weight proteins. An increased β2-microglobulin excretion was found in five workers with a normal urinary protein electrophoresis whereas only the urine of three exposed workers were found to be normal. We have confirmed a previous observation that in the majority of the cadmium-exposed workers with an abnormal electrophoretic pattern or an increased total proteinuria, not only low molecular weight proteins (β2-microglobulin) are excreted in greater amount but also high molecular weight proteins such as albumin and transferrin. Furthermore, in cadmium-exposed workers proteinuria is more closely related to the concentrations of albumin and orosomucoid in urine than that of β2-microglobulin. The change in urinary concentration of total amino acids was less marked than that of protein. The determination of both low and high molecular weight proteins ought to be recommended for detecting renal damage due to cadmium.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00378317
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Circulating immune complexes in infants fed on cow's milk (1978)
    [s.l.] : Nature Publishing Group
    Nature 272 (1978), S. 632-632 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] 1C were detected by their ability to inhibit the agglutinating activity of rheumatoid factor (RF) or purified human Clq, a constituent of the first factor of complement, towards particles coated with human IgG\ As RF, we used the suitably diluted (1/200) serum of a patient with rheumatoid ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/272632a0
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Circulating immune complexes in normal human pregnancy (1977)
    [s.l.] : Nature Publishing Group
    Nature 266 (1977), S. 542-543 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Agglutination inhibition tests were carried out as before7 using latex suspension provided by the Behring Institute (Marburg, FRG). However, human rheumatoid factor (RF) or Clq which failed to react with the immune complexes of pregnancy, were replaced by rabbit RF. RF was induced in rabbits by ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/266542a0
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    Paper (German National Licenses)
    Fulltext
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