Electronic Resource
Oxford, UK
:
Blackwell Publishing Ltd
Clinical and experimental pharmacology and physiology
5 (1978), S. 0
ISSN:
1440-1681
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
1. Prazosin had a marked inhibitory effect on post-synaptic a-receptors in the pithed rat, as measured by the blood pressure response to the cumulative administration of clonidine.2. Prazosin had no inhibitory effect, however, on the pre-synaptic a-receptor, as measured by the clonidine-induced reduction in the tachycardia produced by stimulation of the cardiac nerves.3. These results suggest that prazosin has a selective antagonistic affinity for post-synaptic a-receptors.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1440-1681.1978.tb00705.x
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