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  • 1
    Electronic Resource
    Electronic Resource
    Characteristics of fast excitatory postsynaptic current in bullfrog sympathetic ganglion cells (1979)
    Springer
    Pflügers Archiv 378 (1979), S. 205-212 
    Details
    ISSN: 1432-2013
    Keywords: Excitatory synaptic current ; Time course ; Membrane potential ; Ca2+ ; Sympathetic ganglion cell
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The membrane current underlying the fast excitatory postsynaptic potential (EPSC) of bullfrog sympathetic ganglion cells was studied. The relationship between the EPSC amplitude and membrane potential was linear at negative levels of membrane potential, but deviated from the linearity toward a smaller amplitude at positive levels. The falling phase of EPSC almost followed a single exponential decay. The half-decay time (HDT) of EPSC's increased exponentially with an increase in the negativity of membrane potential. The rise time (RT) was also prolonged slightly with membrane hyperpolarization. Lowering of temperature decreased the EPSC amplitude, lengthened markedly the HDT and increased the slope relating the logarithm of the HDT to membrane potential. Neostigmine (1×10−5 M) prolonged both the RT and HDT. A decrease in Ca2+ concentration caused a marked reduction in the EPSC amplitude, and a slight shortening in the RT and HDT. An increase in Ca2+ concentration significantly prolonged the RT and HDT without altering the slope of the relationship between the HDT and membrane potential, while the amplitude of EPSC was increased slightly. The HDT was independent of EPSC amplitude. It is suggested that the mechanism responsible for closing the ion channels of the nicotinic receptor at the subsynaptic membrane is regulated by membrane potential. The possible mechanisms of the action of Ca2+ on the decay phase of EPSC were discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00592737
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  • 2
    Electronic Resource
    Electronic Resource
    The effect of microstructure on the toughness of ferritic nodular cast iron (1976)
    Springer
    Journal of materials science 11 (1976), S. 723-730 
    Details
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The ductile-brittle transition behaviour in ferritic nodular cast iron appears to depend not only on chemical compositions but also on many microstructural variables. The ferrite grain diameter and the mean free path between graphite nodules are studied here as the main microstructural variables, and the effects of these on toughness are investigated mainly by the instrumented Charpy impact test. The results show that the transition temperature is lowered when the ferrite grain size or the mean free path is decreased. On the other hand, increase in the ferrite grain size or the mean free path leads to a rise in the upper shelf energy in the ductile fracture range. Equations to predict the dynamic lower yield load (P y) and the maximum load transition temperature (T rpm) are derived from the relation for steel dispersed with spheriodal carbides.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01209460
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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