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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 22 (1975), S. 97-111 
    ISSN: 1432-1106
    Keywords: Mossy fibers ; Vestibular afferents ; Vestibular nucleus neurons ; Vestibulo-floccular input ; Semicircular input
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In decerebrate, unanesthetized cats, responses in the flocculus were evoked by electric stimulation of the vestibular nerves and by natural stimulation of horizontal head angular acceleration. Field potentials in the flocculus and intracellular recording from Purkinje cells following vestibular nerve stimulation indicated that the responses were produced by mossy fiber inputs. Field potentials evoked from the contralateral labyrinth were as large as those from the ipsilateral one. There was considerable convergence of bilateral labyrinthine mossy fiber inputs to a Purkinje cell. In view of the effects of incision at the midline of the cerebellum and the brain stem, inputs from the contralateral labyrinth were mainly conveyed through the midline of the brain stem and partly through the midline of the cerebellum. Primary vestibular afferents were involved in the transcerebellar crossed pathway. Fibers of the secondary vestibular neurons projecting to the contralateral flocculus were implicated in the brain stem-mediated pathway and, in part, presumably in the transcerebellar crossed pathway. About one-third of the axon spikes examined in the flocculus responded to horizontal head angular acceleration. Commissural inhibition was observed in more than half of the axon spikes in the flocculus which were presumed to be mono- or polysynaptically activated from the vestibular nerve.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 33 (1978), S. 27-39 
    ISSN: 1432-1106
    Keywords: Horizontal canal afferent ; Resting activity ; Transfer function ; Vestibular nucleus neuron
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Dynamic characteristics of primary vestibular afferents innervating the horizontal semicircular canal were studied in decerebrate, unanesthetized cats. Activities of individual afferent fibers were recorded intracranially by glass micropipettes. Frequency of sinusoidal rotation was varied from 0.014 Hz to 0.42 Hz, and phase and gain properties were examined. All of the fibers recorded fired spontaneously, and their firing rate ranged from 7 to 128 spikes/sec. Regularity of firing, phase lags, and gains were calculated in individual fibers. There was a tendency that the units with high spontaneous firing rates showed regular firing, larger phase lags, and lower gains than the units with low spontaneous firing rates. The transfer function of the system (firing rate of the primary afferent per angular acceleration of the head) was $$\frac{{1.98(0.08s + 1}}{{4.1s + 1}}$$ . A high frequency phase lead component was needed to account for the data obtained, indicating a slight deviation from the relationship predicted by the torsion pendulum model. The present phase properties were compared with those of vestibular nucleus neurons reported previously. It was suggested that a group of vestibular nucleus neurons transmits fairly faithfully the phase properties of primary afferents, and that another group of vestibular nucleus neurons receive additional influences from central structures, exhibiting larger phase lags than primary afferents.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary 7-Chloro-3-(4-methyl-1-piperazinyl)-4H-1,2,4-benzothiadiazine-1,1-dioxide (DU-717) is a new compound having sustained antihypertensive activity in a similar manner to that of hydrochlorothiazide. However, this compound shows neither diuretic nor hyperglycemic effect, being different from those of hydrochlorothiazide or diazoxide.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 34 (1978), S. 885-886 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The effects of enzymatic digestions and physicochemical treatments on an alkali stable polysaccharide, which polymerize fibrinogen, extracted from a strain ofStaphylococcus epidermidis, were observed in the demonstration of gel formation of fibrinogen.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Histochemistry and cell biology 57 (1978), S. 93-96 
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary A simplified method of emulsion coating and development for quantitative electron microscopic radioautography without any special instrument is introduced. Seven grids carrying ultrathin sections are attached to a glass block with double-coated Scotch tape. They are coated with a wire-loop, 2.5 cm in diameter. Ten glass blocks are then stuck on a slide, exposed, developed, fixed and stained simultaneously. Employing this method, the emulsion coating and the following procedures are easily accomplished under an identical condition.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Histochemistry and cell biology 58 (1978), S. 103-111 
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The glycogen of rabbit granulocytes has been studied in glutaraldehyde and osmium tetroxide fixed bone marrow by the periodic acid-thiocarbohydrazide-silver proteinate procedure (PA-TCH-SP). The PA-TCH-SP procedure involved the staining of intracytoplasmic glycogen more densely than the routine lead citrate staining. The PA-TCH-SP procedure demonstrated the intracytoplasmic glycogen in all three kinds of granulocytes. Though a sequence of intensity was observed in each stage of cell maturation, intracytoplasmic glycogen increased generally in accordance with cell maturation in the granulocytes. Functional significance of the glycogen in the granulocytes was discussed in relation to its staining. A very weak reaction in the granules of the granulocytes was described in relation to their contents.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Rabbit bone marrow cells have been studied by means of light-and electron-microscopic radioautography and X-ray microanalysis. Carrier free sulfuric acid was used as the radioactive precursor in this experiment. Immature granulocytes showed more active incorporation than mature ones. Silver grains were observed in the Golgi apparatus and granules in three kinds of granulocytes. Electron-microscopically, immature granules showed the incorporation of inorganic sulfate, while mature ones did not. Sulfur was detected in all kinds of granules of the three granulocyte types by X-ray microanalysis. It is concluded that incorporated inorganic sulfur may be utilized for the synthesis of acid glycosaminoglycans and the sulfur detected by X-ray microanalysis may be that contained in the acid glycosaminoglycan. The sulfur detected in the specific granules of the heterophil probably derives from proteins or polypeptides incorporating sulfur containing amino acids.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Colloid & polymer science 253 (1975), S. 343-343 
    ISSN: 1435-1536
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Molecular genetics and genomics 152 (1977), S. 245-251 
    ISSN: 1617-4623
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Twelve mutants ofPhycomyces blakesleeanus with defects in sporangiophore phototropism (genotypemad) were obtained from a wild type of the (+) mating type by mutagenesis with nitrosoguanidine. These mutants were tested for genetic complementation against standard (+)mad mutants derived from sexual crosses between the isogenic (+) strain and established (-)mad mutants (Ootaki et al., 1974; Eslava et al., 1976). Heterokaryons for complementation tests were obtained by grafting stage I sporangiophores. The (+) mutants were also investigated for their sensory responses such as photoinduction of sporangiophores and avoidance. The mutants were grouped into two classes, based on the phenotypic classification scheme of Bergman et al. (1973). There were eleven class 1.2 mutants and one class 2 mutant. Complementation tests revealed that all eleven class 1.2 mutants carry the genemadC and the class 2 mutant carriesmadD. There was no evidence that any were double mutants. These results are consistent with the phenotypic classification and with the complementation results of themad mutants of the (-) mating type.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 24 (1979), S. 837-852 
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: The breaking mechanism of nylon-6 yarn is investigated, and the breakage of the yarn under simple tensile loading conditions is compared to that of a filament caused by the same loading. The simple model yarn consisting of seven filaments was prepared for this purpose. The yarn was ruptured at a low rate of extension, and the fracture morphologies of the filaments in the yarn were inspected by a scanning electron microscopy. These morphologies are clearly different from those of the filaments broken individually under the same testing conditions used for the yarn. Various kinds of appearances are obtained in the yarn, for example, a large V-shaped notch is observed, the controlled ductile tearing region is developed across the filament at a large angle to its axis, and the ruptured end is expanded into a plane which is perpendicular to its axis. These causes are discussed in detail to understand the breaking mechanism of the yarn.
    Additional Material: 15 Ill.
    Type of Medium: Electronic Resource
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