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  • 1970-1974  (9)
  • 1
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The rate of DNA synthesis in the course of the division cycle in root meristem ofAllium cepa growing under constant temperature and aeration conditions has been studied by means of treatment with AdR, as a specific inhibitor of the synthesis, as well as by the incorporation of tritiated thymidine. The one-hour treatment with AdR or tritiated thymidine was given at various hours in the course of the interphase of a synchronous population of binucleate cells induced by caffeine. In the case of AdR, sensitivity to the inhibition of DNA synthesis was studied by recording the delays produced by the treatment in the appearance of biprophases and bitelophases. The selection by the use of caffeine, of spontaneously synchronous populations of cells going through the telophase and becoming binucleate and the detection of the first biprophases in the subsequent mitosis provide a highly synchronized system with which to study the incorporation of tritiated thymidine during the interphase. The curves representing sensitivity to the inhibition of DNA synthesis by AdR and the rate of tritiated thymidine incorporation coincide, so that we can regard the delays, under our conditions, as proportional to the rate of DNA synthesis at the moment of the AdR treatment. This rate, in the S period, was found to be variable by both methods, being higher in the first and the last thirds of the S period (S1 and S3) and lower in the middle third (S2).
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Mineralogy and petrology 19 (1973), S. 149-172 
    ISSN: 1438-1168
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Description / Table of Contents: Zusammenfassung Die mächtigen und weit ausgedehnten, fast völlig unbekannten känozoischen Vulkanite SW-Boliviens lassen sich in vier Einheiten gliedern: a) Laven und pyroklastische Gesteine der Julaca- und Rondal-Formation (Miozän), b) Ignimbrite der Quehua superior-Formation (Miozän/Pliozän), c) Ignimbrite der Ignimbrit-Formation (Pliozän bis Alt-Pleistozän), d) Laven und Pyroklastika der Stratovulkan-Formation (Pleistozän bis Holozän). Von diesen känozoischen Vulkaniten, die gleich alt wie jene im benachbarten Chile sind, werden erstmals von 33 Problen Hauptelement- und Spurenelement-Analysen (Rb, Sr, Co, Cu, Ni, Zn und Zr) veröffentlicht. Die Laven der Stratovulkan-Formation zeigen eine starke petrochemische Ähnlichkeit zu den unterlagernden Ignimbriten. Rhyodacite und Dacite (KlassifikationStreckeisen) herrschen sowohl unter den Laven als auch unter den Ignimbriten vor. Unter den Laven der großen Stratovulkane wurden keine eigentlichen Andesite gefunden; der basischste Typ hat latiandesitische Zusammensetzung. Diese nahe Übereinstimmung in der Hauptelement- und Spurenelement-Konzentration läßt darauf schließen, daß die Magmen der Stratovulkan- und der Ignimbrit-Formation unter annähernd gleichen regionalen physikochemischen Bedingungen gebildet wurden. Feldbeobachtungen, vor allem aber die petrochemischen und mineralogischen Daten, weisen auf eine Entstehung dieser Schmelzen durch partielle Anatexis von Krustenmaterial hin. Hinweise für eine Differentiation dieser Schmelzen aus einem basaltischen high-alumina Stammagma wurden nicht gefunden. Auf Grund der stärkeren Azidität der Laven der Stratovulkan-Formation SW-Boliviens verglichen mit denen der annähernd gleich alten Vulkanite der nord-chilenischen “Andesit”-Formation wird gefolgert, daß die Magmen-Genese unter dem Altiplano SW-Boliviens in höheren Krusten-Niveaus erfolgte als im benachbarten Nord-Chile. Wir nehmen, gestützt auf geophysikalische Messungen, an, daß die Magmen des Untersuchungsgebietes in Tiefen zwischen 9 und 26 km gebildet wurden. Diese Auffassung steht in Einklang mit der geophysikalisch nachgewiesenen Krustendicke von 76 km unter dem Altiplano.
    Abstract: Résumén Se presentan análisis de 33 elementos mayoritarios y datos de elementos trazas de Rb, Sr, Co, Cu, Ni, Zn y Zr de rocas volcánicas modernas del SW de Bolivia. Estos volcanitos ampliamente distribuídos de edad Cenozoica que son contemporáneas a los del Norte de Chile, puede ser divididos en cuatro secuencias: lavas y piroclastos de las Formaciones Julaca y Rondal (Mioceno?), tobas e ignimbritas de la Formación Quehua Superior (Mio-Plioceno), ignimbritas de la Formación Ignimbrítica (Plio-Pleistoceno bajo), y lavas y piroclastos de la Formación Estrato-volcanes (Pleistoceno-Holoceno). Las lavas de la Formación estrato-volcanes, son obviamente similares en petroquímica, respecto a las ignimbritas subyacentes. Las lavas y las ignimbritas son de composición riodacíticas y dacíticas. Ninguna andesita verdadera fué encontrada entre las lavas de los grandes estrato-volcanes; el tipo más básico es de composición lati-andesítica. La pequeña variación en elementos mayoritarios y trazas sugiere que las ignimbritas y los magmas de los estrato-volcanes fueron generados bajo esfuerzos físico-químicos regionales similares. Datos de campo, petrográficos y petroquímicos indican para estos magmas un origen por fusión total o parcial de las rocas de la corteza. No se encontró ninguna evidencia de que los magmas de los estrato-volcanes se diferenciaron de un magma parental basáltico con un alto contenido de alúmina. Tomando en cuenta la composición más ácida de las lavas de los estratos-volcanes del sudoeste boliviano, comparadas con aquellas de la Formación Andesítica del Norte de Chile se cree que la generación del magma ocurrió en los niveles más altos de la corteza. La profundidad de fusión de la corteza del sudoeste del Altiplano boliviano se presume que varía en un rango de 9 a 26 kilómetros. Esta inferencia es una de las más consistentes de acuerdo a datos geofísicos por los cuales el espesor de la corteza alcanzaría a los 76 kilómetros por debajo del Altiplano.
    Notes: Summary 33 major element analyses and Rb, Sr, Co, Cu, Ni, Zn, and Zr trace element data of the young volcanic rocks of SW-Bolivia are presented. These widespread volcanics of Cenozoic age which are contemporaneous with those in the adjacent northern Chile can be divided into four sequences: lavas and pyroclastics of the Julaca and Rondal Formations (Miocene), ignimbrites of the Quehua superior Formation (Miocene/Pliocene), ignimbrites of the Ignimbrite Formation (Pliocene to lower Pleistocene), and lavas and pyroclastics of the Strato-volcano Formation (Pleistocene to Holocene). The lavas of the Strato-volcano Formation are obviously similar in petrochemical respect to the underlying ignimbrites.Rhyodacites anddacites are predominating both among the lavas and the ignimbrites. No realandesite was found among the lavas of the great strato-volcanoes; the most basic type is oflatiandesitic composition. The small variance in major and trace element bulk composition suggests that the ignimbrite and stratovolcano magmas were generated under regional similar physico-chemical constraints. Field, petrographic, and petrochemical data favour an origin of these magmas by melting or partial melting of crustal rocks. No evidence was found that the strato-volcano magmas differentiated from a high-alumina basalt parent magma. On account of the more acidic composition of the lavas of the SW-Bolivian strato-volcanoes as compared with that of the north-Chilean “Andesite” Formation it is believed that magma generation occurred in higher crustal levels than that of the “Andesite” Formation of northern Chile. The depth of crustal melting beneath the SW-Bolivian altiplano is thought to be in the range of 9 and 26 kilometres. This suggestion is believed to be most consistent with geophysical data according to which the thickness of the crust amounts to 76 km beneath the altiplano.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Virchows Archiv 362 (1974), S. 13-21 
    ISSN: 1432-2307
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The microscopic morphology, histochemistry and electron microscopy of a non-ossifying fibroma of the upper metaphysis of the femur in a sixteen-year-old girl, is presented. The authors describe a fibroblastic cell type as the basis of the neoplasia which transforms itself into a foam cell loaded with lipids. Histochemically it is characterized by high activity in alkaline phosphatases, ATP-ases, fructose 1–6 diphosphatase and NADH-NADPH tetrazolio reductases. Electron microscopy identifies extremely active fibroblastic cells with a synthesis of proteic and lipid material which transforms them into foam cells. The lipids appear irregularly enveloped in laminar systems. There is also a deposit of hemosiderine in certain fibroblasts. Non-ossifying fibroma differs from the metaphyseal fibrous bone defect as the fibroblasts show a higher activity for alkaline phosphatase and lipids are stored in the cytoplasma.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 27 (1971), S. 972-974 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Resumen Se determinan los números de fase en poblaciones meristemáticas en equilibrio dinámico, donde permanecen constantes a 1 o largo del tiempo. Se estudia su evolución en presencia de tres tratamientos que producen bloqueo en tiempos diferentes del ciclo de división celularinterfase, profase y metafase.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Resumen El uso de una población binucleada sincrónia inducida por cafeína 0.1% en el meristemo de la raiz deAllium cepa L., nos ha permitido demostrar que una solución de kinetina 0.5 ppm mas ácido indol acético 0.001 ppm acorta tanto la interfase como la mitosis, y valorar este acortamiento por medida directa.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract 3′-deoxyadenosine, applied to meristematic populations, proves to be a drug which causes an accumulation of cells in the prophase. Analysing its effects, we find that cells in prophase continue to go through their chromosome cycle and thus that the specific effect of the drug is to block the rupture of the nuclear membrane, giving rise to a process of endomitosis in the cells treated. If the drug is applied to synchronous, labelled cells, analysis of its effects reveals that they occur at the prophase level, while the remaining stages of mitosis, if not arrested in the prophase, proceed normally. The data here brought forward as to the effects of 3′-deoxyadenosine, like those relating to the effects of other drugs which block RNA synthesis at the prophase level, suggest that this stage in the cell division cycle is of great importance in the evolution of the mitotic process.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The degree of synchrony in the course of the interphase periods G1, S and G2 and in the initiation of mitosis in the several nuclei of each cell of a polynucleate population induced by treatment with 0.1% caffeine, in root meristems of Allium cepa, through inhibition of cytokinesis in two successive cell divisions is analysed by means of labelling with 3H-thymidine.—The S period is initiated simultaneously in all the nuclei of each polynucleate cell, which supports the hypothesis of a factor present in the cytoplasm that is responsible for inducing DNA synthesis.—However, all the nuclei in a polynucleate cell do not pass from the S period to the G2 period simultaneously, those surrounded by the greatest amount of cytoplasm, generally the outer nuclei, being the first to complete the S period (“early nuclei”) and beginning the prophase before their fellow-nuclei in the same cell (“late nuclei”).—From the metaphase onwards, however, all the nuclei in a polynucleate cell continue to develop synchronously. The synchronizing mechanism has a twofold aspect: the shortening of the G2 period in the “late nuclei” and the lengthening of it in the “early ones” and, on the other hand, an arrest of prophase in the “early nuclei” until the “late ones” have caught up, which suggests the existence of an inhibiting factor produced by the “late nuclei” capable of acting upon the early ones through the cytoplasm.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    New York : Wiley-Blackwell
    Die Makromolekulare Chemie 168 (1973), S. 19-26 
    ISSN: 0025-116X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Description / Table of Contents: Methoxylierte 4-vinylbenzophenone wurden radikalisch mit Styrol in benzolischer Lösung copolymerisiert. Die Zusammensetzung der Produkte konnte mittels 1H-NMR-Spektren bestimmt werden. Die Copolymerisationsparameter für die radikalische Copolymerisation wurden berechnet; hierbei zeigten die methoxylierten p-Vinylbenzophenone eine größere Reaktivität als Styrol. Diese 4-Vinylbenzophenonhomo- und -copolymeren haben keine schützende Wirkung gegen UV-Bestrahlung. Die hierfür notwendige Bedingung ist das Vorhandensein einer Hydroxylgruppe in ortho-Stellung zur Carbonylgruppe. Deshalb untersuchten wir die partielle Entmethylierung der 4-Vinyl-2′-methoxy-benzophenonpolymeren. Ihre saure Behandlung gab 2′-Hydroxyderivate. Das UV-Spektrum des erhaltenen Poly(4-vinyl-2′-hydroxy-4′-methoxybenzophenons) zeigt eine schützende Wirkung gegen natürliches Tageslicht an.
    Notes: Les monomères cités ont été copolymérisés radicalairement dans le benzene avec le styrène. La composition des copolymères a été déterminée à partir de leurs spectres NMR. Les constantes r1 et r2 été détérminée d calculdes; dans ce cas, les p-vinylbenzopédnones méthoxy-lées ont une plus grande réactivité que le styrene. Les homo et copolymkres de ces p-vinyl-benzophdnones n'ont aucun effet protecteur contre le rayonnement UV. La condition nécessaire pour obtenir cet effet est la pédsence d'un groupement hydroxyle en position ortho par rapport au groupement carbonyle. La déméthylation partielle des polyméres des vinyl-4 méthoxy-2′ benzophénones a été étudiée dans ce but. Cette réaction a permis d'obtenir en particulier la poly(viny1-4 hydroxy-2′ mdthoxy-4′ benzophenone) dont le spectre UV indique un effet protecteur contre la lurnière naturelle.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    New York : Wiley-Blackwell
    Die Makromolekulare Chemie 167 (1973), S. 147-154 
    ISSN: 0025-116X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Description / Table of Contents: Es wurden methoxylierte p-Vinylbenzophenone dargestellt, indem man die aus p-Chlorstyrol bereitete magnesiumorganische Verbindung mit methoxylierten Benzaldehyden reagieren ließ und die dabei erhaltenen p-Vinylbenzhydrole oxidierte. Die Monomeren ließen sich radikalisch in Lösung polymerisieren Dabei entstanden Polymere hohen Mol.-Gew., die in einer späteren Arbeit teilweise entmethyliert und deren Absorptionseigenschaften im UV-Gebiet eingehend untersucht werden sollen.
    Notes: Les p-vinyl benzophénones méthoxylées ont été synthétisées par action du chlorure de p-vinyl phényl magnésium sur les benzaldéhydes méthoxylés suivie de l'oxydation des p-vinyl benzhydrols obtenus. Les monoméres ont été polymérisés par procédure radicalaire en solution. Cette réaction conduit, dans le cas de la benzophénone diméthoxylée, à des polyméres de grandes masses. Ces polymères seront partiellement déméthoxylés dans un prochain travail afin de faire apparaître les propriétés d'absorbeurs UV.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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