ISSN:
1432-0878
Keywords:
Fibrinogen
;
Erythrocyte
;
Endothelium
;
Tricomplex flocculation
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary During a study of lung surfactant, incidental findings of significance regarding blood and capillaries were obtained. Tricomplex flocculation revealed stained material at the erythrocyte surface. This material had two components: (1) flocculant deposits in the cortical cytoplasm and (2) erythrocyte associated globules (EAG's) showing a distinctive internal fine structure. The EAG's were immediately apposed to the outer leaflet of the plasmalemma as a variably incomplete extraneous coat. Pinocytotic vesicles also contained stainable material having an internal fine structure which was identical to the EAG. Of the various plasma proteins studied, only fibrinogen stained with the morphology of the EAG. On the basis of this distinctive morphology it is suggested that the EAG and the vesicular contents are fibrinogen or a derivative thereof.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00226613
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