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  • 1970-1974  (1)
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  • 1970-1974  (1)
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    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 20 (1973), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Except for the crystalline deposits of hypoxanthine found in skeletal muscle of patients with congenital xanthine oxidase deficiency (xanthinuria) there are few reports concerning oxypurines in the mammalian tissues (Parker, Snedden and Watts, 1969, 1970). Since it is difficult to separate hypoxanthine from xanthine in biological fluids (Simmonds and Wilson, 1967), the distribution of hypoxanthine in mammalian tissues is not known in detail.This paper shows that cubic or rod crystals of C5H4ON4are easily isolated from calf brain by column chromatography with ion exchange resin Amberlite CG120 and their identity with hypoxanthine was shown by means of nuclear magnetic resonance and mass Spectrometry.
    Type of Medium: Electronic Resource
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