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  • 1970-1974  (2)
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Material
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Year
  • 1
    Electronic Resource
    Electronic Resource
    Studies with divinyl ether-maleic anhydride and foot-and-mouth disease vaccines in swine (1974)
    Springer
    Archives of virology 46 (1974), S. 334-340 
    Details
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Mice treated with divinyl ether-maleic anhydride (DVE/MA) 7 days before, 2 days before, or simultaneously with foot-and-mouth disease (FMD) viral antigens (aqueous or oil emulsified) were more resistant to virus infection and released antibody earlier than mice treated with antigen alone. Simultaneous treatment of swine with these antigens plus DVE/MA resulted in a slightly enhanced early antibody response, which, in a test with oil-emulsified antigen, was not associated with an early induced antiviral resistance to FMD. In general, the primary and secondary antibody responses to oil antigen plus DVE/MA were the same as in control swine receiving the antigen alone. However, swine sensitized with aqueous antigen plus DVE/MA responded faster and developed higher antibody titers after a secondary treatment with aqueous antigen than swine treated similarly but without DVE/MA.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01240075
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Reaction of swine to oil-adjuvanted inactivated foot-and-mouth disease virus vaccine inoculated by intramuscular and subcutaneous routes (1971)
    Springer
    Archives of virology 35 (1971), S. 364-377 
    Details
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Local reactions at inoculation sites of swine vaccinated with foot-and-mouth disease antigens emulsified with oil adjuvant were examined at 7, 14, 32, 45, 62 and 90 days postinoculation. The serologic data indicate that either the subcutaneous or intramuscular route, as well as the different inoculation sites selected induce a similar antibody response. Lesions at all inoculation sites were characterized by subacute and chronic granulomatous tissue reaction and the continuous presence of oil vacuoles. There is little doubt that some degree of reaction at the site of inoculation is to be expected and thus the site and route are of utmost importance in reducing the possibility of a carcass blemish.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01241917
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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