ISSN:
1432-0878
Keywords:
Avian thrombocytes
;
5HT
;
Reserpine
;
Osmiophilic granules
;
Degranulation
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary Ultrastructural observations of domestic fowl thrombocytes were made with special reference to their intracellular storage site of 5HT. Using a modified method for sampling blood and isolating thrombocytes, a characteristic structure was confirmed in the cytoplasm; the structure was highly osmiophilic, rough-surfaced and quite larger than 5HT granules observed in mammalian platelets. Disappearance of the structure, associated with a marked reduction of 5HT content, was caused by in vivo treatment with reserpine; this indicated its function to store the amine. From various morphological patterns indicative of stepwise advancement of degranulation, it was concluded that the 5HT-storing organelle is the multigranular body, which contains smooth-surfaced granules aggregated with fine filamentous structures.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00335298
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