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  • 1970-1974  (1)
  • 1
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Unilateral explants of rat adrenal medulla grown in the anterior chamber of the eye were studied with light and electron microscopy. The surviving chromaffin cells are in proximity to the abundant vessels at 21 days after explantation. However, the typical arrangement of anastomosed cellular cords, such as can be always seen in the normal medulla, is replaced here by clusters, cords and irregular groups of cells. Two types of chroma & cells can be described. The predominant cells are polygonal or elongated in shape and have polymorphous and elongated norepinephrine-positive granules. The other type, less numerous, has a pale cytoplasm with round chromafh cells. This type is norepinephrine negative. Several cytological characteristics of some of the chromaffin cells are also described. These morphological observations are in agreement with the biochemical findings previously published and confirm that a signscant decrease of epinephrine cells occurs in the explant.
    Type of Medium: Electronic Resource
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