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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 336 (1974), S. 1-14 
    ISSN: 1435-2451
    Keywords: Diverticulosis ; Diverticulitis ; Incomplete Diverticle
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Ausgehend von den pathogenetischen Erkenntnissen der letzten Jahre wird auf die besondere Bedeutung des inkompletten Divertikels für das Syndrom Divertikulitis hingewiesen. Die lymphoepitheliale Struktur dieser mit dem kompletten Divertikel vergesellschafteten Form erklärt die Neigung zu chronischen, rezidivierend aufflackernden Entzündungen, die zu disseziierenden Phlegmonen der Darmwand mit konsekutiven Darmwandperforationen führen können. Die pathogenetisehe Bedeutung des inkompletten Divertikels liegt in der Schrittmacherfunktion für die Komplikationen der Divertikulitis. Der Nachweis inkompletter Divertikel im Colonkontrasteinlauf an Hand indirekter und direkter Zeichen ist ein wichtiges Indiz für die Prognose der Erkrankung. Eine konservative Therapie wird in diesen Fällen zum Scheitern verurteilt sein, da sie die schleichende Progredienz der Erkrankung nicht aufhalten kann. Nur die frühzeitige, ausreichend bemessene Resektion kann einen nachhaltigen Heilungserfolg sichern. Das Risiko dieses Eingriffes liegt mit 2,2% heute im Bereich des therapeutisch Vertretbaren.
    Notes: Summary Based on the pathogenetic knowledge of diverticular disease the importance of incomplete diverticula is elucidated. The lymphoepithelial tissue structure of incomplete diverticula indicates the tendency for chronic inflammatory disease, which leads to dissecting phlegmons of the wall of large bowels. Perforation of the colon may occur. The pathogenetic importance of incomplete diverticula is seen in the pacemakerfunction for complications of diverticulitis. The radiological proof by barium enema shows indirect and direct signs of incomplete diverticula. This is an important feature in diagnosis and prognosis. Conservative therapy is usually of little value because of the chronic advance of this disease. Only early and extensive resection of large bowel proves compatible success. In view of the complication the surgical risk — 2,2% — is accountable.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-2013
    Keywords: Abdominal Vagal Afferents ; Vagovagal Reflex ; Blood Pressure ; Respiratory Reflexes ; C-Fibres
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In 65 urethan anesthetized rats low frequency (1–30 Hz) electrical afferent stimulation of the abdominal vagus elicited cardiovascular and respiratory reflexes, which were eliminated by bilateral cervical vagotomy: 1. Heart rate decrease of 1.5 to 55%, mean 13.5±1.9%. 2. Sinusarrhythmia and lengthening of the av-conduction time. Two cases of 2∶1 av-block could be observed. 3. Respiratory rate reduction of an average of 15%. 4. Initial inspiratory apnea of 0.7 to 7 sec duration at stimulation frequencies above 9 Hz. 5. Biphasic blood pressure alteration with an initial slight decrease and a following more pronounced rise. This biphasic type was found to be constituted of two components: a) a depressor response with a threshold of 2 Volts, maximum effect at 6 Hz stimulus frequency. b) a pressor response with a threshold of 3 Volts, maximum effect at 20 Hz stimulus frequency. Type a) and type b) responses could be found in a few cases independently. It is shown, that arithmetical addition of these two types leads to the construction of the biphasic type. Two functional fibre groups of the afferent vagus were discussed. Atropine had no effect on the alteration of respiratory rate and blood pressure, only the bradycardia could be eliminated.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 336 (1974), S. 15-23 
    ISSN: 1435-2451
    Keywords: Rat ; Splenectomy ; Gastric Ulceration ; Increase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung An Ratten wurde der Einfluß von Splenektomie auf Magensaftsekretion und Ulcusentstehung untersucht. Sowohl nach “restraint-stress” als auch Pylorusligatur wiesen die splenektomierten Tiere eine ausgeprägte Steigerung der Ulcuszahl und -größe gegenüber den Kontrolltieren auf. In der Magensaftanalyse waren dagegen die Werte der splenektomierten Tiere gegenüber den scheinoperierten nur geringgradig gesteigert. — Als mögliche Ursache der vermehrten Ulcusanfälligkeit nach Splenektomie wurde eine Veränderung lokaler, nicht säuresekretorischer Faktoren der Magenwand diskutiert.
    Notes: Summary In Splenectomiced rats incidence of gastric ulceration was compaired with control groups. Restraint stress and ligation of pylorus was used as model. Splenectomiced rats do show an higher incidence in both models. Both frequency and extension of gastric ulcer were accumulated significantly. Analysis of gastric secretion was only unessentially raised in comparisom to control-groups. Change of protective factors of stomach as possible reason is discussed.
    Type of Medium: Electronic Resource
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