ISSN:
0006-3525
Keywords:
Chemistry
;
Polymer and Materials Science
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Polymerization of γ-ethyl DL-glutamate N-carboxy anhydride (NCA) in DMF has been carried out at various temperatures and with the use of tri-n-propylamine as the initiator. It was found that on decreasing the polymerization temperature the reaction rate is lowered but the molecular weight and the helix content of the final polymer are enhanced. An overall activation energy of ∼4 kcal/mole has been found for the polymerization process. Preliminary experiments carried out on the polymerization of γ-benzyl D-glutamate NCA in DMF and with tri-n-propylamine as the initiator showed a strong depressing effect of the CO2 evolved during the polymerization, both on the reaction rate and on the molecular weight of the polymer. All data are interpreted in terms of the Bamford-Swarc mechanism.
Additional Material:
5 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/bip.360100110
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