ISSN:
0018-019X
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Univalent copper is stabilized in aqueous medium by the non-protophilic ligand CH3CN, allowing ligand displacement reactions to be investigated as if a stable CuI-hydrate did exist. Under these conditions the formation of CuI-complexes with imidazole and its derivatives has been studied in polar solution in the absence of CuII. Imidazole (ImH) acts upon CuI as a bidentate ligand forming polynuclear chains according to the equation Histamine reacts in the same way, i. e. the coordination number of CuI does not exceed 2; by comparison of the complexes of CuI with histamine and its N-methyl-derivatives it is shown that no six-membered chelate - which sterically would be possible - is built up. Trigonal as well as tetrahedral coordination of CuI - i. e. chelate formation - in dilute polar solutions are confined to π- or d-acceptor ligands, e. g. bipyridine or methionine. Conclusions are drawn from this on the requirements for redox-active copper in proteins.
Additional Material:
7 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/hlca.19700530125
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