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  • 1970-1974  (2)
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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    International archives of occupational and environmental health 26 (1970), S. 157-166 
    ISSN: 1432-1246
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The authors examined the lungs of 29 coal miners with various grades of pneumoconiosis for histological changes and for the content of silica, hydroxyproline and hexosamine. The changes found in lungs were classified into the following groups: interstitial focal pneumoconiosis (simple pneumoconiosis), progressive massive fibrosis and coniotuberculosis. The changes found in bronchi occurred in foci and the most serious of them were noticed in the neighborhood of peribronchial granulomas that adhered to or proliferated in bronchial walls. The content of silica in progressive massive fibrosis lesions was three times higher than that in the pulmonary tissue with simple pneumoconiosis. The walls of bronchi of the 1st, 2nd and 3rd order contained comparatively very little silica—only one third of the content found in the pulmonary tissue with simple pneumoconiosis. The content of hydroxyproline in progressive massive fibrosis lesions was equal to that in the pulmonary tissue with simple pneumoconiosis despite the fact that dust was accumulated in the lesions. The content of hydroxyproline in the bronchi of coal miners with pneumoconiosis was equal to that found in control subjects of the same age; it decreased from the bronchi of the 1st order to the bronchi of the 3rd order but was always higher there than in pulmonary tissue.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    International archives of occupational and environmental health 29 (1972), S. 291-311 
    ISSN: 1432-1246
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Es wurde der Gesundheitszustand von 82 MÄnnern und 103 Frauen mit einem Durchschnittsalter von 39 Jahren überprüft. Die Untersuchten waren in Futtermischereien tÄtig und einer hohen Staubkonzentration ausgesetzt. Der Staub enthÄlt neben organischen Bestandteilen verschiedene Mineralkomponenten und bakterielle und mykotische Mikroorganismen. Bei den Untersuchten wurden nach den Kriterien der WHO chronische Bronchitiden in höherer Zahl gefunden als bei der Normalpopulation und den übrigen landwirtschaftlichen Arbeitern, und zwar bei den MÄnnern in 43%, bei den Frauen in 18%. In der Mischerei mit der höchsten Verstaubung wurde bei den MÄnnern chronische Bronchitis sogar in 72% festgestellt — signifikant hÄufiger als bei den MÄnnern aus den übrigen Mischereien, bei Ausschlu\ der Einflüsse von Alter und Rauchen. Im Sputum der Untersuchten fand sich in reichlicheren Mengen eine Pilzflora als bei der Normal-population und das übliche Bakterienspektrum. Die Bakterien waren in 65% resistent gegenüber Antibiotica der Tetracyclinreihe, welche den Futtermischungen beigemengt werden. Bei 11% aller Untersuchten bestanden durch berufliche Staubirritation bedingte Kontaktdermatitiden.
    Notes: Summary The general health of 82 men and 103 women with an average age of 39 years was investigated. These persons all work in feed-mixing plants and are exposed to high concentrations of dust. Aside from organic components, this dust contains various minerals and also bacterial and fungal microorganisms. According to the standards of WHO, the incidence of chronic bronchitis was much higher in this group than in the normal population or other farm workers, in men by 43% and in women by 18%. In those departments with the highest concentration of dust, chronic bronchitis was present in 72% of all men, significantly more than in the men of other departments (disregarding the effects of age and smoking). The saliva of this group showed an increased level of fungal components as compared to the normal population. The bacterial components were normal, but 65% of them were resistant to antibiotics of the tetracycline group (a group contained in the feed mixtures). In 11% of the group dust irritation evidently had caused various types of topical dermatites.
    Type of Medium: Electronic Resource
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