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  • 1970-1974  (2)
  • 1
    Electronic Resource
    Electronic Resource
    ABSENCE OF DIRECT ACTION OF INSULIN ON METABOLISM OF THE ISOLATED PERFUSED RAT BRAIN (1971)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 18 (1971), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The ability of insulin to influence directly the metabolism of the mammalian brain has been evaluated with an isolated, perfused rat brain preparation. Insulin was added to the perfusion fluid or was injected into the rat from which the isolated brain preparation was subsequently made. The spontaneous electrical activity of the brain, the rate of cerebral glucose consumption and the rate of efflux of K+ from the brain were not affected by insulin. We conclude that insulin either does not act directly on the brain or that its action is very small and/or very slow in comparison with its action on other tissues. We suggest that the effects on brain metabolism reported to occur after administering insulin and glucose to the intact animal may be secondary to the large stimulation of the metabolism of the liver and/or other organs.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1971.tb00225.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Synaptic contacts from nodes of Ranvier in the granular layer of the frog cerebellum (1972)
    Springer
    Journal of neurocytology 1 (1972), S. 255-262 
    Details
    ISSN: 1573-7381
    Keywords: nodes of Ranvier ; synapses ; cerebellum
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The ultrastructure of nodes of Ranvier was examined in the granular layer of the cerebellum ofRana nigromaculata. Many of the nodes in the layer were modified to form synaptic contacts with dendrites, probably of granule cells. The axoplasm of bulbous presynaptic nodes contained a central bundle of neurofilaments, peripheral clouds of agranular spherical vesicles, and mitochondria. Multiple active zones were usually seen. Up to four dendrites were found in synaptic contact with a single node. Adjacent dendrites synapsing at a node were occasionally connected by apunctum adhaerens. Some nodes extended slender processes of 0.2 to 0.4 μm in diameter ending in a terminal bouton in synaptic contact with a dendrite.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01099937
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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