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  • 1
    Electronic Resource
    Electronic Resource
    Chemical Properties of Amorphous Metals (1978)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Materials Research 8 (1978), S. 215-233 
    Details
    ISSN: 0084-6600
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.ms.08.080178.001243
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  • 2
    Electronic Resource
    Electronic Resource
    EFFECTS OF CALCITONIN ON THE SECRETION OF PANCREATIC JUICE INDUCED BY DOPAMINE, SECRETIN AND PANCREOZYMIN (1976)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental pharmacology and physiology 3 (1976), S. 0 
    Details
    ISSN: 1440-1681
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: 1. Effects of calcitonin on dopamine-, secretin- and pancreozymin-induced pancreatic secretion were investigated in the isolated blood-perfused canine pancreas.2. The volume of pancreatic secretion induced by pancreozymin given intra-arterially (i.a.) was decreased by an i.a. infusion of 1 u/min of calcitonin, but that induced by dopamine or secretin given i.a. was not affected by calcitonin treatment.3. Amylase concentration in pancreatic juice either in spontaneous secretion in the resting state or in that of stimulated secretion by pancreozymin was decreased approximately 30% by calcitonin treatment, but amylase concentration in pancreatic juice induced by dopamine or secretin was not affected by calcitonin treatment.4. Calcitonin had no effect on bicarbonate concentration in pancreatic juice stimulated by these secretagogues.5. Calcium concentration in pancreatic juice in the resting state was reduced about 36% by calcitonin treatment. Calcitonin caused a decrease in a calcium concentration in the pancreozymin-induced secretion, but did not cause any change in the dopamine- or secretin-induced one.6. These results suggest that calcitonin may affect the secretory mechanism of the acinar cells but not that of the ductular cells, and that the acinar cells are active even in the resting state.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1440-1681.1976.tb00600.x
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  • 3
    Electronic Resource
    Electronic Resource
    EFFECTS OF GLUCAGON ON PANCREATIC SECRETION IN THE DOG (1976)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental pharmacology and physiology 3 (1976), S. 0 
    Details
    ISSN: 1440-1681
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: 1. The effects of glucagon on the secretion of pancreatic juice were investigated using blood-perfused canine pancreas preparations.2. Intravenous administration of glucagon (3–30 μg/kg) to the donor dog elicited a dose-dependent increase in pancreatic secretion. Intra-arterial administration of glucagon (10–100 μg) into the perfused pancreas also elicited increased secretion.3. There were slight increases in amylase concentration of the pancreatic juice with the largest doses of glucagon given by either route.4. Glucagon-induced secretion was not modified by treatment with phentolamine, propranolol, atropine, guanethidine, tetrodotoxin, haloperidol, prostaglandin F2a or calcitonin.5. The results suggest that glucagon acts directly on the exocrine cells of the canine pancreas.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1440-1681.1976.tb00591.x
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  • 4
    Electronic Resource
    Electronic Resource
    ANTIARRHYTHMIC PROPERTIES OF 5-(3-TERT-BUTYLAMINO-2-HYDROXY)PROPOXY-3,4-DIHYDRO-CARBOSTYRIL HYDROCHLORIDE (OPC- 1085), A NEWLY SYNTHESIZED, POTENT β-ADRENORECEPTOR ANTAGONIST (1977)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental pharmacology and physiology 4 (1977), S. 0 
    Details
    ISSN: 1440-1681
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: 1. The antiarrhythmic properties of 5–(3-tert-butylarnino-2-hydroxy)propoxy-3,4-dihydrocarbostyril hydrochloride (OPC-1085) were compared with those of propranolol and pindolol using various kinds of preparations for experimental arrhythmia in dogs.2. Although OPC-1085 was the most potent drug to antagonize adrenaline-induced arrhythmia in animals anaesthetized with either pentobarbitone sodium or halothane, it was scarcely effective on ouabain-induced arrhythmia in pentobarbitone sodium anaesthetized animals.3. When these compounds were administered intravenously to conscious dogs 24 h after two-stage ligation of the anterior descending artery, ectopic ventricular beats of coronary ligation-induced arrhythmia were reduced while regular sinus beats were simultaneously increased.4. OPC-1085 was very effective on aconitine-induced arrhythmia in dogs anaesthetized with pentobarbitone sodium. The effective dose was similar to that of propranolol but about fifteen times less than that of pindolol.5. It is concluded that different potencies among these β-adrenoreceptor antagonists against various kinds of experimental arrhythmias cannot be simply deduced from any one of the following properties; β-adrenoreceptor antagonism, intrinsic myocardial stimulation, local anaesthetic and so-called quinidine-like effects.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1440-1681.1977.tb02684.x
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  • 5
    Electronic Resource
    Electronic Resource
    Maturation defect of a temperature-sensitive mutant of western equine encephalitis virus (1977)
    Springer
    Archives of virology 53 (1977), S. 209-219 
    Details
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The defective step of a temperature-sensitive mutant of western equine encephalitis virus, which synthesize viral RNA but not mature virus at the restrictive temperature, was studied. Cells infected with the mutant virus at the restrictive temperature synthesized the same intracellular viral RNA as that in wild type infection. Cells infected with the mutant at the restrictive temperature formed three proteins (E1, E2 and C) which migrated to positions identical with those of purified virions and a precursor protein of E2 (PE2). The mutant virus was also able to form cytoplasmic nucleocapsids sedimenting at 140S as in the case of wild type infection. On the other hand, cells infected with the mutant could not induce a significant amount of hemadsorbing ability and the ability induced at the permissive temperature disappeared immediately after shifting up to the restrictive temperature. These results suggested that the mutant virus produced a defective envelope protein responsible for hemagglutination at the restrictive temperature. Owing to the incompleteness of the modification of the cell plasma membrane by the envelope proteins, viral nucleocapsids in the mutant infected cells could not bind to the plasma membrane.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01314665
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  • 6
    Electronic Resource
    Electronic Resource
    Comparison of Β-Adrenergic blocking activity of dichloroisoprenaline (H 56/28, I.C.I. 50172, LB46), methoxamine (MJ 1999) and propranolol in the canine femoral vascular bed (1969)
    Springer
    Cellular and molecular life sciences 25 (1969), S. 1155-1156 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Die blockierende Wirkung intra- arteriell verabreichter,Β-adrenergischer Mittel wurde am femoralen Gefässgebiet des Hundes untersucht. DCI, H 56/28 und LB 46 per se regten den arteriellen Blutstrom mit zunehmender Dosierung an, während Methoxamin in umgekehrter Weise wirkte. Eine hemmende Wirkung auf den durch Isoprenalin angeregten Blutstrom fand sich in folgender Reihenfolge: LB 46≧H 56/28 〉 Propranolol 〉 MJ 1999=DCI. I.C.I. 50172 und Methoxamin fehlt diese Wirkung.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01900246
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  • 7
    Electronic Resource
    Electronic Resource
    Linkages between chromophore and apoprotein in the biliverdin-protein of the scales of big blue parrotfish, Scarus gibbus Rüppell (1977)
    Springer
    Cellular and molecular life sciences 33 (1977), S. 583-584 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary On the basis of the amino acid composition of the chromophore peptides, it can be assumed that Asp, Ser and 1/2 Cys are located near the biliverdin chromophore. Experiments for splitting of the chromophore lead us to expect a thioether bond in the linkages between biliverdin and apoprotein.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01946509
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  • 8
    Electronic Resource
    Electronic Resource
    Enhanced urea excretion, probably by forming inclusion compound with lutidine (1966)
    Springer
    Cellular and molecular life sciences 22 (1966), S. 520-520 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Die Harnstoffausscheidung wurde durch 2,6-Lutidin i.v. wahrscheinlich über die Bildung der Einschlussverbindung gesteigert. Die isomere Substanz blieb wirkungslos.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01898665
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  • 9
    Electronic Resource
    Electronic Resource
    Beta-adrenergic blocking effect of dichloroisoprenaline (DCI), (H 56/28, I.C.I. 50172, LB 46), methoxamine (MJ 1999) and propranolol on the sinus node activity of the dog heart (1969)
    Springer
    Cellular and molecular life sciences 25 (1969), S. 1156-1157 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Der Hemmungseffekt siebenΒ-adrenergischer Blockierungsmittel auf positive chronotrope Wirkung bei zunehmender Dosierung von Isoprenalin wurde durch Verabreichung in die Sinusknotenarterie vergleichend untersucht. Reihenfolge der Wirksamkeit: LB 46, H 56/28, Propranolol〉I.C.I. 50172, DCI〉MJ 1999〉Methoxamin.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01900247
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  • 10
    Electronic Resource
    Electronic Resource
    Effect of cordycepin on the replication of western equine encephalitis virus (1976)
    Springer
    Archives of virology 52 (1976), S. 341-345 
    Details
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Cordycepin (3′-deoxyadenosine) inhibited viral RNA synthesis in the replication of western equine encephalitis virus, thereby causing a reduction of virus production. The rate of inhibition of viral RNA synthesis was dependent on drug concentration and the period of treatment with the drug. These results suggest that the virus RNA synthesizing system is sensitive to the drug.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01315623
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