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  • 1
    ISSN: 1432-0428
    Keywords: Diabetes in old age ; anaesthesia ; Tolbuta-mide ; insulin ; hypoglycaemia ; insulin resistance ; insulin allergy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Substitution of insulin for a dietary regime with or without oral hypoglycaemic agents prior to operation is, despite its general use, often not satisfactory because of lack of time and leads frequently to hypoglycaemia and sometimes to excessive insulin-antibody production. We therefore administered 1.0 g of Tolbutamidei.v. together with at least 100 g of carbohydrates per day to 36 non-insulin dependent diabetic patients, and compared the results with those of 28 similiar cases switched to insulin preoperatively in the usual way (I), and those of 27 patients receiving insulin before, during and after the operation (II). Interventions in the group on Tolbutamide i.v. (III) were more severe and lasted longer than those in the control groups. Blood-sugar levels on the operation day rose to 209 ± 76 mg% in the Tolbutamide group, (Control group I 203 ± 57, II 186 ± 52). Hypoglycaemia was observed in the control groups only. The method proposed avoids unnecessary insulin treatment and its consequences, and can be recommended, with correct selection of patients, for further evaluation during minor and more extensive operations.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 46 (1968), S. 1008-1010 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary The mean cortisol secretion rate was significantly elevated in fifteen patients with acromegaly. The increase was especially pronounced in untreated patients while in treated ones the mean value was close to that of normal persons. Calculated as secretion rate per kg body weight there was also a significant elevation in patients with untreated acromegaly. Conversely, in treated patients the value was in the low normal range. In four patients with active acromegaly the cortisol secretion rate per kg body weight was significantly higher than in those with an inactive, untreated pituitary process. The corticosterone secretion rate in nine investigated patients with acromegaly was also significantly increased, both in absolute terms and expressed per kg body weight.
    Notes: Zusammenfassung Die mittlere Cortisolsekretion war bei 15 Akromegaliepatienten signifikant erhöht. Die Steigerung war besonders ausgeprägt bei den unbehandelten Patienten, während sich der Mittelwert bei den behandelten dem der Normalpersonen annäherte. Bezogen auf das Körpergewicht fand sich bei den unbehandelten Akromegalen ebenfalls eine signifikant erhöhte Cortisolsekretion. Bei den behandelten lag sie dagegen im untersten Normbereich. Bei vier Patienten mit einer floriden Akromegalie ließ sich gegenüber denjenigen mit einem unbehandelten, inaktiven HVL-Prozeß eine signifikant erhöhte Cortisolsekretion pro kg Körpergewicht nachweisen. Die Corticosteronsekretion war bei neun untersuchten Patienten absolut und bezogen auf das Körpergewicht signifikant gesteigert.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 46 (1968), S. 618-619 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Experiences with a New Test-strip for Bloodsugar Determination. Blood-sugar values were estimated in 643 in- and out-patients with the new test-strip “Haemo-Glucotest”. Blood-sugar determinations performed with the Auto-Analyzer (Hoffmann) served as an objective control. The treatment of out-patients was determined according to the values of the “Haemo-Glucotest” strip and before the Auto-Analyzer results arrived. 80% of the estimated values varied from the Auto-Analyzer results by less than ± 20 mg-%. Preliminary therapy had to be modified in only 6% of the patients. The precision of the determination depends upon illumination and the ability for color discrimination of the person working with the test-strip. The “Haemo-Glucotest” strip is not only suitable for detection of hyperglycemia and hypoglycemia, but also for control of therapy in diabetic out-patients.
    Notes: Zusammenfassung Der Teststreifen Hämo-Glucotest wurde an 643 stationär und ambulant behandelten Diabetikern erprobt. Als objektiver Vergleich dienten die Blutzuckerbestimmungen nachHoffmann im Autoanalyzer. Die Behandlung der ambulanten Patienten wurde nach den Ergebnissen des Hämo-Glucotest vor Kenntnis der Autoanalyzerbestimmung festgelegt. 80% der geschätzten Werte wichen um weniger als ± 20 mg-% von den durch Autoanalyzer bestimmten Blutzuckerwerten ab. Die nach den Testergebnissen vorläufig festgelegte Therapie der ambulanten Patienten brauchte nur in 6% der Fälle korrigiert zu werden. Die Genauigkeit der Bestimmung ist von den Beleuchtungsverhältnissen während des Tests und vom Farbunterscheidungsvermögen des Untersuchers abhängig. Der Teststreifen eignet sich nicht nur zur Erfassung von Hypo- und Hyperglykämien, sondern auch für eine orientierende Blutzuckerbestimmung bei der ambulanten Einstellungskontrolle von Diabetikern.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    European archives of oto-rhino-laryngology and head & neck 188 (1967), S. 292-308 
    ISSN: 1434-4726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 205 (1967), S. 472-475 
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The muonic 2p-1s transitions in16O and18O have been measured with a Ge detector, with the 3d-2p transitions of Cl as reference line. Therms radii of18O and16O differ by 3.5±0.8 per cent as compared with 4.0 per cent according to the A1/3 law.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 227 (1969), S. 311-319 
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Energies and yields of nuclearγ-rays accompanyingπ-mesic X-ray spectra have been measured. Theγ-lines arise either in nuclei of the atomic number of the target, or in nuclei of smaller atomic numbers. The first kind ofγ-rays are due mainly to inelastically scattered neutrons produced by pion capture in another target nucleus (secondary process), whilst the second kind are due to ordinary nuclear capture (primary process).
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Archives of gynecology and obstetrics 206 (1968), S. 431-436 
    ISSN: 1432-0711
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Untersuchungen an isolierten Uteri (Ratte, Maus) und beim Menschen während Kaiserschnitten ergaben, daß Oxytocinwährend undunmittelbar nach Halothan-Exposition in der Lage ist, eine Halothan bedingte Wehenhemmung und Basaltonussenkung aufzuheben. Methergin war dagegen nicht in der Lage,während oderunmittelbar im Anschluβ an die Halothan-Narkose die Wehenhemmung und Basaltonussenkung zu durchbrechen, und eine erneute Wehentätigkeit mit Basaltonusanstieg herbeizuführen. Halothan vermochte jedoch seinerseits dosisabhängig eine Oxytocin oder Methergin induzierte hypertone Wehentätigkeit zu durchbrechen und eine Wehenhemmung und Basaltonussenkung zu erzeugen. Zur Frage des Fehlens metherginsensibler Receptoren am Ratten-Uterus und zur Frage der Angriffspunkte und Wirkungsmechanismen von Halothan, Oxytocin und Methergin wurde Stellung genommen.
    Abstract: Résumé Des expériences exécutées sur l'utérus isolé (rat, souris) ainsi que chez l'homme lors de césariennes ont démontré quependant etjuste après exposition à l'Halothane (Fluothane) l'oxytocine est capable de compenser l'inhibition des contractions et la baisse du tonus de base dues à l'Halothane. Au contraire avec la Méthergine il n'a pas été possible, ni chez l'homme ni chez l'animal, de compenser l'inhibition des contractions et la baisse du tonus de basependant ou juste après exposition à l'Halothane et de provoquer à nouveau le travail avec élévation du tonus de base. De sa part pourtant l'halothane a été capable, en dépendance de la dose, de couper le travail utérin hypertonique provoqué par l'oxytocine ou la Métbergine et de provoquer une inhibition des contractions et une baisse du tonus de base. Il est pris position envers la possibilité du manque de récepteurs sensibles à la Méthergine dans l'utérus du rat ainsi qu'envers la question des points d'attaque et du mode d'action de l'Halothane, de l'oxytocine et de la Méthergine.
    Notes: Summary Experiments on isolated uteri of rats and mice and observations of women during caesarian sections showed, that Oxytocin, during and immediately after Fluothane exposition, is able to abolish the Fluothane induced inhibition of labour contraction and the reduction of the basal tone. In contrast, Methergin was found to be unable to abolish the Fluothane induced effects under the same experimental conditions. Fluothane itself, however, depending on doses given, was able to stop the Oxytocin or Methergin induced hypertonic labour contractions and to create a labour inhibition and to reduce the basal tone. The question as to the absence of Methergin sensitive receptors in the rat uterus and the problem of the reaction points and mechanism of action of Fluothane, Oxytocin and Methergin are discussed.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The differentialΒ-γ directional correlation and the integralΒ-(circularly polarizedγ) correlation in the decay of170Tm have been measured on the same metallic source.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Archive of applied mechanics 36 (1968), S. 335-347 
    ISSN: 1432-0681
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Summary The formation of a shock wave by the gradual steepening of an acceleration wave in plane motion or in motion with cylindrical or spherical symmetry is studied for a gas which undergoes an arbitrary number of thermodynamic relaxation processes. The thermodynamic state of the relaxing gas is described implicitly by introducing additional independent thermodynamic variables together with relaxation equations for these variables. The conservation of mass and momentum leads to relations for the propagation of acceleration discontinuities. Combined with the thermodynamic equations these relations yield an expression for the variation with time of the amplitude of an acceleration wave. This in turn leads to a condition for shock wave formation. The results are generalizations of a result given byBürger for the time of formation of a plane shock wave. They are, moreover, in formal agreement with results given byVarley et al. for acceleration waves in viscoelastic materials with fading memory for which the thermodynamic equations of state are given explicitly in form of functionals.
    Notes: Übersicht Die Aufsteilung von Beschleunigungswellen zu Verdichtungsstößen wird für ebene, zylinder- und kugelsymmetrische Bewegung eines Gases untersucht, in dem beliebig viele thermodynamische Relaxations-vorgänge ablaufen. Die von dem relaxierenden Gas durchlaufenen thermodynamischen Zustände werden implizit durch Einführung zusätzlicher unabhängiger thermodynamischer Variablen und Vorgabe von Relaxations-gleichungen für diese Variablen beschrieben. Kombination der Zustandsgleichungen mit den aus Kontinuitätsund Impulssatz folgenden Bedingungen für die Ausbreitung einer Unstetigkeit in der Beschleunigung ergibt einen Ausdruck für die Zeitabhängigkeit der Amplitude einer Beschleunigungswelle. Hieraus kann eine Bedingung für die Verdichtungsstoßentstehung hergeleitet werden. Die Ergebnisse sind Verallgemeinerungen eines vonBürger für ebene Bewegung gefundenen Resultats für die Entstehungszeit eines Stoßes. Sie stimmen formal überein mit den vonVarley et al. angegebenen Resultaten für Beschleunigungswellen in viskoelastischen Materialien mit schwindendem Gedächtnis, deren Zustandsgleichungen explizit in Funktionalform vorgegeben sind.
    Type of Medium: Electronic Resource
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