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Oral collagen biosynthesis in the guinea pig (1967)

Claycomb, C. K. ; Summers, G. W. ; Dvorak, E. M.

Oxford, UK : Blackwell Publishing Ltd

Journal of periodontal research 2 (1967), S. 0

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ISSN: 1600-0765

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Medicine

Notes: Collagen biosynthesis, as measured by conversion of 3-4 3H-proline to 3H-hydroxyproline, was studied in guinea pig oral tissue and skin during normal growth, ascorbic acid depletion and following administration of ascorbic acid to scorbutic animals. Collagen breakdown in oral and skin tissue of normal animals was determined by measuring the depletion of 14C-hydroxyproline over a seven month period of time. Oral collagen demonstrated a high level of metabolic activity, thus providing biochemical support to the histo-pathological concept that periodontal tissues exist in a state of continuous wound healing and repair.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1111/j.1600-0765.1967.tb01879.x

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Amino-acid Composition of Collagen isolated from the Oral Cavity of the Sperm Whale (1965)

SUMMERS, G. W. ; CLAYCOMB, C. K.

[s.l.] : Nature Publishing Group

Nature 206 (1965), S. 1046-1047

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ISSN: 1476-4687

Source: Nature Archives 1869 - 2009

Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics

Notes: [Auszug] Freshly frozen specimens of periodontal ligament and gingiva were obtained from an adult sperm whale at the whaling station, Coal Harbor, B.C. Collagen was isolated as gelatine by the method of Neuman and Logan3, Samples of soluble gelatine were precipitated at 2 C by the addition of 20 per cent ...