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  • 1995-1999  (10)
  • 1965-1969  (12)
  • 1910-1914  (1)
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Year
  • 1
    Electronic Resource
    Electronic Resource
    Oxford UK : Blackwell Science Ltd.
    Journal of neurochemistry 72 (1999), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract : Metabotropic glutamate receptors (mGluRs) are coupled toG protein second messenger pathways and modulate glutamate neurotransmissionin the brain, where they are targeted to specific synaptic locations. As partof a strategy for defining the mechanisms for the specific targeting of mGluR1α, rat brain proteins which interact with the intracellular carboxyterminus of mGluR1 α have been characterized, using affinitychromatography on a glutathione S-transferase fusion protein thatcontains the last 86 amino acids of mGluR1 α. Three of the proteinsspecifically eluted from the affinity column yielded protein sequences, two ofwhich were identified as glyceraldehyde-3-phosphate dehydrogenase andβ-tubulin ; the other was an unknown protein. The identity of tubulin wasconfirmed by western immunoblotting. Using a solid-phase binding assay, themGluR1 α-tubulin interaction was shown to be direct, specific, andsaturable with a KD of 2.3 ± 0.4 μM. In addition, mGluR1 α, but not mGluR2/3 or mGluR4, could be coimmunoprecipitated from solubilized brain extracts with tubulin using anti-β-tubulin antibodies. However, mGluR1 α could not be coimmunoprecipitated with the tubulin binding protein gephyrin, nor could it be coimmunoprecipitated with PSD95. Collectively these data demonstrate that the last 86 amino acids of the carboxyl-terminal tail of mGluR1 α are sufficient to determine its interaction with tubulin and that there is an association of this receptor with tubulin in rat brain.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Inorganic chemistry 7 (1968), S. 335-338 
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 34 (1912), S. 36-49 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 72 (1965), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 90 (1968), S. 6382-6384 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: SUMMARY: The effectiveness of 1-naphthaleneacetic acid (SNA) and 2,4,5-trichlorophenoxyacetic acid (2,4,5-T) in markedly retarding further ripening of pineapple fruit and thus extending its marketable life as a fresh fruit has been demonstrated. The effects are evident at different stages of maturity and ripeness, different fruit densities, and from both pre-harvest and post-harvest applications. As little as 1 ppm of 2,4,5-T has noticeable effect, and 100 ppm appears optimum for senescence delay. For SNA, 500 ppm is an optimum level for dipping fruit. A brief wetting of the fruit is adequate. The crowns remain in better condition when not treated with growth regulator. Refrigeration can supplement the effect of the chemical in retarding senescence. Lower temperatures can retard some of the changes which even treated fruit will show, and the chemical can retard ripening changes that otherwise may take place, albeit slowly, under normal refrigeration of pineapple fruit.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: An unstable compound with an intense odor of “burnt pineapple” was isolated as a major component of a pineapple flavor concentrate. This compound was tentatively identified as 2,5-dimethyl-P-hydroxy-3(2H)-furanone (I).
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 30 (1965), S. 0 
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Nitrogenous constituents of developing pineapple fruit were determined at weekly intervals on two lots of fruit in 1958 and four lots in 1963. Some analyses on shell tissue were included. The fraction of nitrogen in the flesh of the fruit not precipitated by trichloroacetic acid or by heating fell during the prematuration period, then rose during the final weeks of development. By contrast, the concentration of heat-soluble nitrogen in the shell fell throughout fruit development. Many of the constituent free amino acids in the juice also showed a minimum concentration during the middle of the developmental period, or maturation. The notable exception to the nitrogen trends was methionine, which was generally absent until onset of final ripening but present in considerable amounts thereafter. Protein concentration rose during the first weeks after cessation of flowering, then dropped somewhat during the remainder of fruit development. Little or no protease activity was found in the flesh of fruit shortly after flowering, but the enzyme then appeared abruptly and remained at a high level during fruit development, dropping only during the final period of ripening. Peroxidase activity was high in the young fruit and fell steadily throughout fruit development, reaching a minimum during ripening. At this time, the activity was only a third that of the fruit shortly after flowering. The trends in nitrogenous constituents reinforced the earlier suggestion of several discrete physiological stages in the development of the pineapple fruit.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 30 (1965), S. 0 
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Developing pineapple fruit were analyzed at weekly intervals, two lots in 1958 and four lots in 1963. Both spring and summer harvests were included. Soluble solids, sucrose, reducing sugars, titrable acids, pH, citric acid, and alcohol-insoluble solids in the flesh show consistent patterns of change during fruit development. The soluble solids and pH of the shell tissues also relate to fruit development, but differ from those in the flesh tissues. By contrast, malic acid and ascorbic acid appear to vary in association with short-term weather conditions, not with stage of fruit development. The trends in carbohydrate and acid constituents of pineapple fruit suggest several discrete physiological stages: prematuration; maturation, beginning about seven weeks before normal ripeness; ripening, beginning two to three weeks before the half-yellow stage of ripeness; and senescence.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 30 (1965), S. 0 
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Pigments in the shell and flesh tissues of developing pineapple fruit were analyzed at weekly intervals on four different lots of fruit ripening in the spring and in the summer of 1963. Chlorophyll in the shell showed little change until final ripening began. It then disappeared during the final two weeks of development. Anthocyanin and chalcone compounds in the shell fell off steadily throughout fruit development. The carotenoid pigments in the shell showed a small downward trend during development, followed by a small rise during senescence of the fruit, after the chlorophyll had disappeared. In the flesh, however, the carotenoids showed quite marked changes. These pigments fell until about seven weeks before ripeness, then rose markedly during the final two-week ripening period. The trends in plant pigments are consistent with suggestions from earlier studies on nitrogenous, carbohydrate, and acid constituents of the pineapple during development, indicating that there are several discrete physiological stages for the fruit.
    Type of Medium: Electronic Resource
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