Springer Online Journal Archives 1860-2000
Abstract The body weight and morphometric parameters of the state of the pancreatic insular apparatus (the relative percentage of islet tissue, of A- and B- cells, the number of islets) in fetuses and the adult offspring of healthy female rats and male rats with alloxan diabetes were studied. No change in these parameters was found, indicating that under these conditions the genetic systems of the males are undamaged and that these lesions are not transmitted to the progeny. On the basis of these findings and of the importance of diabetes in the female in the development of insular deficiency in the progeny demonstrated previously, the role of the environment in which the fetus develops in the formation of the diabetes is emphasized.
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