Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Methotrexate decreases thymidine kinase activity
    Amsterdam : Elsevier
    Biochemical and Biophysical Research Communications 187 (1992), S. 522-528 
    Details
    ISSN: 0006-291X
    Keywords: [abr] APRT; adenine phosphoribosyltransferase ; [abr] AZT; azidothymidine, zidovudine ; [abr] DH; dehydrogenase ; [abr] GPRT; guanine phosphoribosyltransferase ; [abr] IC"5"0; dose required for 50% decrease in activity ; [abr] MTX; methotrexate ; [abr] TdR; thymidine ; [abr] dTMP; thymidylate ; [abr] i.p.; intraperitoneally ; [abr] s.c.; subcutaneously ; [abr] t"1"/"2; the time required for 50% decrease in activity
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/S0006-291X(05)81525-6
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Methotrexate decreases thymidine kinase activity
    Amsterdam : Elsevier
    Biochemical and Biophysical Research Communications 187 (1992), S. 522-528 
    Details
    ISSN: 0006-291X
    Keywords: [abr] APRT; adenine phosphoribosyltransferase ; [abr] AZT; azidothymidine, zidovudine ; [abr] DH; dehydrogenase ; [abr] GPRT; guanine phosphoribosyltransferase ; [abr] IC"5"0; dose required for 50% decrease in activity ; [abr] MTX; methotrexate ; [abr] TdR; thymidine ; [abr] dTMP; thymidylate ; [abr] i.p.; intraperitoneally ; [abr] s.c.; subcutaneously ; [abr] t"1"/"2; the time required for 50% decrease in activity
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/S0006-291X(05)81525-6
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Targeted and non-targeted actions of anti-cancer drugs
    Amsterdam : Elsevier
    Advances in Enzyme Regulation 34 (1994), S. 71-89 
    Details
    ISSN: 0065-2571
    Keywords: [abr] 5-FU; 5-fluorouracil ; [abr] AC; acivicin ; [abr] CdR kinase; deoxycytidine kinase ; [abr] DHFR; dihydrofolate reductase ; [abr] FdUMP; fluorodeoxyuridylate ; [abr] GPRT; guanine phosphoribosyltransferase ; [abr] IMP DH; inosine 5'-monophosphate dehydrogenase ; [abr] MTX; methotrexate ; [abr] SHMT; serine hydroxymethyltransferase ; [abr] TAD; thiazole-4-carboxamide adenine dinucleotide ; [abr] TK; TdR (thymidine) kinase ; [abr] TR; tiazofurin, 2-β-d-ribofuranosylthiazole-4-carboxamide ; [abr] dTMP synthase; TS, thymidylate synthase ; [abr] dTMP; deoxythymidylate ; [abr] dUMP; deoxyuridylate ; [abr] taxol (paclitaxel) NSC 125973
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0065-2571(94)90009-4
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Schwermetallchelate von α-Cyano-β-amino-dithioacrylsäureestern (1986)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 543 (1986), S. 186-191 
    Details
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Heavy Metal Chelates of α-Cyano-β-amino-dithioacrylatesThe inner metal chelates of PdII, NiII, CoIII, and AgI with α-cyano-β-amino-dithioacrylates have been prepared. The coordination of the dithioester group and the amine nitrogen (S/N-coordination) has been proved by the chemical shift of the S2p and N1s electron binding energies in the ESCA spectra.
    Notes: Es wurden Innerchelatmetallkomplexe des PdII, NiII, CuII, CoIII und AgI mit α-Cyano-β-amino-dithioacrylsäureestern dargestellt. Die Koordination der Dithiocarbonester-gruppierung und des Aminstickstoffs (S/N-Koordination) wird durch die chemische Verschiebung der S2p- und N1s-Elektronenbindungsenergien in den ESCA-Spektren bewiesen.
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19865431222
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Zur Komplexbildung von N-(Thiocarbamoyl)benzamidinen (1985)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 523 (1985), S. 153-160 
    Details
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Complex Formation of N-(Thiocarbamoyl) benzamidinesN-(Thiocarbamoyl)benzamidines 1 and N-(Thiocarbamoyl)-N′-phenyl-benzamidines 2 form in alcoholic solutions with Ni2+, Cu2+, Pd2+, Co3+, and Ag+ ions well crystallized chelates 1a —h and 2a—h, respectively, with N/S coordination.The X-ray photoelectron spectra evidence the NH group as ligator in the case of chelates of 1 and the increased donor capacity compared with the isosteric oxygen ligator atom bound to nickel. This is confirmed by d-1H-n.m.r. spectroscopy analyzing the value of ΔGc≠ for the rotational barrier for the Et2N group of 1a
    Notes: N-(Thiocarbamoyl)banzamidine 1 und N-(Thiocarbamoyl)-N′-phenyl-benzamidine 2 bilden mit Ni2+-, Pd2+-, Co3+- und Ag+-Ionen in alkoholischer Lösung kristalline Innerchelatkomplexe1a—h und 2a—h mit N/S-Koordination.Aus ESCA-Spektren wird im Falle der Chelate von 1 als Haftgruppe NH nachgewiesen und ihre höhere Donorfähigkeit im Vergleich mit dem isosterne Sauerstoffhaftatom gegenüber Nickel fest-gestellt. Dies wird durch d-1H-NMR-spektroskopisch bestimmte Werte von ΔGc≠ für die behinderte Rotation der Et2N-Gruppe an 1 a unterstützt.
    Additional Material: 3 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19855230419
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...