ISSN:
1434-4475
Keywords:
Reissert compound
;
Intramolecular cyclization
;
2-Benzyloxy-3-methoxy-8H-dibenzo-[a,g]-8-quinolizione
;
(±)-Bharatamine
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Summary Alkylation of theReissert compound1 by methyl 2-bromomethylbenzoate (2) followed by spontaneous intramolecular cyclization affords dibenzo [a,g]quinolizinone4 which in turn can be reduced to benzyl ether5 by LiAlH4/NaBH4. Debenzylation of5 by ethanolic HCl furnishes the title compound6 in improved total yield.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00807398
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