ISSN:
0947-3440
Schlagwort(e):
Baker-Venkataraman rearrangement
;
3-Methoxyflavones
;
Phase-transfer catalysis
;
Catalytic transfer hydrogenation
;
Transesterifications
;
Chemistry
;
Organic Chemistry
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Chemie und Pharmazie
Notizen:
Some 3-methoxyflavones were known to possess antipicornavirus properties. In order to study the structure-activity relationship, attempts to prepare 3-methoxyflavone by literature methods were unsuccessful. We have modified the Baker-Venkataraman rearrangement, using a solid base and a phase-transfer catalyst. After searching optimal reaction conditions and a study of the intermediate formed in a model reaction, good yields were obtained for the 3-methoxyflavones 7, 21-32. Further some of the corresponding 7-O-n-butyl derivatives 4, 33-37 could be isolated as side products.
Zusätzliches Material:
5 Tab.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1002/jlac.199719971020
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