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  • Articles: DFG German National Licenses  (2)
  • 4-aminopyridine  (1)
  • Age  (1)
  • 1
    Electronic Resource
    Electronic Resource
    A transient outward rectification in the cat sympathetic preganglionic neuron (1987)
    Springer
    Pflügers Archiv 408 (1987), S. 207-208 
    Details
    ISSN: 1432-2013
    Keywords: Transient outward current ; Potassium current ; 4-aminopyridine ; Post-spike hyperpolarization ; Spinal cord
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Intracellular recordings were made from sympathetic pregangionic neurons of the intermediolateral nucleus, in the slice of the T3 segment of the cat spinal cord. Depolarization to −60 mV from membrane potentials more negative than −75 to −80 mV caused a transient outward rectification which decayed in 0.5–2.0s. The rectification was sensitive to changes in K concentation, was abolished by 4AP (2 mM), and was unaffected by low Ca (0.25 mM), Co (2 mM), Ba (1 mM), TEA (20 mM) or intracellular Cs. These properties suggest that the rectification is due to a transient K-current similar to the A-current described in other neurons.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00581354
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Morphometric study of glomerular basement membrane and proximal tubular basement membrane in adult thin basement membrane disease (1999)
    Springer
    Clinical and experimental nephrology 3 (1999), S. 290-295 
    Details
    ISSN: 1437-7799
    Keywords: Key words Thin basement membrane disease (TBMD) ; Glomerular basement membrane (GBM) ; tubular basement membrane ; Age
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background. Thin basement membrane disease (TBMD) is a benign hereditary glomerulopathy with a diffuse attenuation of glomerular basement membrane (GBM). Whether the development of renal basement membranes other than GBM is normal in TBMD has not yet been resolved. Methods. We performed a morphometric study to measure the thickness of GBM and proximal tubular basement membrane (P-TBM) in 44 adult patients with TBMD and in 10 adult diseased controls confirmed to have minor glomerular abnormalities. Results. There was a significant difference between the patients with TBMD and the diseased controls in the thickness of the GBM; however, there was no significant difference between the two groups in the thickness of the P-TBM. In the patients with TBMD, the thickness of the GBM was unchanged with age, but the thickness of the P-TBM increased with age, as did that in the diseased controls. Conclusion. Our morphometric study clarified that the development of P-TBM was normal in the patients with TBMD.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s101570050049
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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