ISSN:
1432-1335
Keywords:
Immuno-chemotherapy
;
Interferonβ
;
Interferonγ
;
Metastatic colorectal cancer
;
Ifosfamide
;
Mafosfamide
;
5-Fluorouracil
;
Mitomycin C
;
Carboplatin
;
Bleomycin
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Three phase I/II trials were performed in patients with metastatic colorectal cancer using immunochemotherapy — a combination of recombinant interferonβ undγ with low doses of cytostatic drugs. The third regimen, consisting of a cytostatic component containing 5-fluorouracil plus carboplatin plus mitomycin C besides the interferons, produced a high remission rate of 47%: 14/30 patients responded. The tolerability of this protocol was good and it could be administered on an out-patient basis.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01613230
Permalink
