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  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Psychopharmacology 48 (1976), S. 83-90 
    ISSN: 1432-2072
    Schlagwort(e): Atropine sulfate ; Cholinergic ; Neocortical EEG ; Ethyl alcohol ; Rabbit EEG ; Hippocampal EEG ; Hippocampal RSA ; Thetarhythm
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Electroencephalographic (EEG) activity was recorded from hippocampus and neocortex of rabbits. It was found that movement, movement-related 6–12 Hz rhythmical slow actvity (RSA), and movement-related neocortical desynchronization were unaffected by intravenous atropine sulfate but depressed by ethyl alcohol (ethanol). Slower 4–8 Hz immobility-related RSA and immobility-related neocortical desynchronization produced by sensory stimulation (visual, auditory, tactle, vestibular) were relatively unaffected by ethanol even at high (0.1–0.2 g-%) blood alcohol levels, but were abolished by atropine sulfate. The results provide evidence for the idea of two pharmacologically separable cortical activating systems and suggest that ethanol has a greater effect on noncholinergic than cholinergic systems.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    ISSN: 1432-2072
    Schlagwort(e): Dopamine ; Feeding ; EEG ; 6-Hydroxydopamine ; Norepinephrine ; Self-Stimulation ; Temperature
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract The effects of intraventricular injections of 6-Hydroxydopamine (OHDA), Dopamine (DA) and dl-Norepinephrine (NE) were examined in rats. Daily treatments of OHDA (400 Μg) suppressed self-stimulation, eating and drinking and produced hyper-responsivness to handling and synchronization of cortical EEG during periods of non-movement when tests were made 23–24 h following daily treatments. DA (1000 Μg) inhibited only eating while NE (400 Μg) treated animals were similar to animals receiving only control injections. On tests made in the first 5 h following treatment NE and DA produced hypothermia, inhibition of grooming, synchrony of cortical EEG and suppression of the amplitude of hippocampal EEG each with a similar time course. Following OHDA treatment on the first day hypothermia and inhibition of grooming occurred but these changes were not observed following subsequent treatments.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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