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Digitale Medien

Erythrocyte 2,3-bisphosphoglycerate concentrations and haemoglobin glycosylation in normoxic Type 1 (insulin-dependent) diabetes mellitus (1984)

Roberts, A. P. ; Story, C. J. ; Ryall, R. G.

Springer

Diabetologia 26 (1984), S. 389-391

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ISSN: 1432-0428

Schlagwort(e): Haemoglobin A1c ; Type 1 diabetes ; oxygen dissociation curve ; 2,3-bisphosphoglycerate ; p50

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Summary Increased erythrocyte 2,3-bisphosphoglycerate concentrations are associated with increased haemoglobin glycosylation in patients with Type 1 diabetes mellitus who have no cause or symptoms of hypoxic stress. This change in 2,3-bisphosphoglycerate metabolism is additional to its response to changes in circulating haemoglobin concentration. Statistical analysis of data showed that erythrocyte 2,3-bisphosphoglycerate concentration did not correlate with the absolute concentration of circulating haemoglobin A1c, but with the proportion of haemoglobin glycosylated. This finding is consistent with the hypothesis that it is changes in the position of the erythrocyte oxygen dissociation curve which modulate the increase in 2,3-bisphosphoglycerate synthesis upon haemoglobin A1c formation.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00266043

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Digitale Medien

The invariant manifold of beam deformations (1993)

Roberts, A. J.

Springer

Journal of elasticity 30 (1993), S. 1-54

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ISSN: 1573-2681

Schlagwort(e): elastic beam theory ; subcentre invariant manifolds ; dynamical systems ; 73C02 ; 73C10 ; 35A35 ; 58G40

Quelle: Springer Online Journal Archives 1860-2000

Thema: Maschinenbau , Physik

Notizen: Abstract The subcentre invariant manifold of elasticity in a thin rod may be used to give a rigorous and appealing approach to deriving one-dimensional beam theories. Here I investigate the analytically simple case of the deformations of a perfectly uniform circular rod. Many, traditionally separate, conventional approximations are derived from within this one approach. Furthermore, I show that beam theories are convergent, at least for the circular rod, and obtain an accurate estimate of the limit of their validity. The approximate evolution equations derived by this invariant manifold approach are complete with appropriate initial conditions, forcing and, in at least one case, boundary conditions.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00041769

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