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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 42 (1992), S. 151-154 
    ISSN: 1432-1041
    Keywords: Antidiabetic drugs ; drug utilization ; health care systems ; Spain ; DDD
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The consumption of antidiabetic drugs in a Spanish region (Extremadura) in the period 1986–1987 has been investigated by the “defined daily dose” (DDD) method. The study was done in three health care systems in the region: civil servants (“Mutualidad de Funcionarios Civiles del Estado: MUFACE”) armed forces group (“Instituto Social de las Fuerzas Armadas: ISFAS”) and the national system (“Instituto Nacional de la Salud: INSALUD”). The total consumption of antidiabetic drugs varied three-fold, ranging from 5,73 DDD per 1000 inhabitants per day (3,71 DDD per 1000 inhabitants per day for oral antidiabetic drugs and 2,02 DDD per 1000 inhabitants per day for insulin) in the civil servant group to 15,82 DDD per 1000 inhabitants per day (12 DDD per 1000 inhabitants per day for oral antidiabetic drugs and 3,82 DDD per 1000 inhabitants per day for insulins) in the armed forces. The differences were more pronounced for oral antidiabetics than for insulins. The utilization of insulin among the civil servants was about half of that by the two other groups. Of oral antidiabetics, sulphonylureas were the most frequently used by the three groups, and within them glibenclamide accounted for more than half of the DDDs, while biguanides were scarcely used in any group. The differences are difficult to assess, since they could be due to several factors, such as age-differences in the population studied, different prescribing habits, and differences in sociocultural level. The results justify further comparative studies of drug utilization in different health systems within the same region.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Applied physics 61 (1995), S. 111-114 
    ISSN: 1432-0630
    Keywords: 81.15.Fg ; 68.55.Nq ; 71.25.Mg ; 82.65.My
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract Amorphous carbon (a-C) films obtained by pulsed-laser ablation of graphite have been investigated by X-ray Absorption Spectroscopy (XAS). The onset of 1s →σ * transitions in the films lies in the gap between theπ * andσ * bands in graphite and very close to the absorption edge of diamond, indicating a high content ofsp 3 hybridization. A sharp feature at this onset is observed and assigned to a core exciton insp 3-hybridized disordered C atoms. Its shift of 0.5 eV with respect to the core exciton in diamond is probably due to a higher localization of the excited electron induced by disorder. A small peak coming from C−H bonds at the surface is observed and its intensity inereases with the amount ofsp 3-hybridized atoms in the sample. This can be easily explained by associating a higher amount of dangling bonds at the surface to a highersp 3 content. Polarization-dependent XAS measurements show that the angular distribution of these C−H bonds has a mean value close to the normal to the surface.
    Type of Medium: Electronic Resource
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