ISSN:
1573-9171
Keywords:
dehydration
;
phenylsulfinyl chloride
;
sulfinic esters
;
Δ9-pregnanes
;
9α-hydroxypregnanes
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract The approaches to the synthesis of various 16α,17α-disubstituted pregna-4,9-dien-3,20-diones from the corresponding 9α-derivatives with labile epoxide, dioxolane, and oxathiolane ringsD′ have been studied. The transformation has been found to proceed efficiently when the 9α-sulfinic esters are used at the intermediate stage and then elimination of sulfinic acid by TsOH/SiO2 is carried out.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00698968
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