ISSN:
1433-8491
Keywords:
ACTH cortisol and dose response
;
ACTH infusion
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The authors examined the dose response relationship between plasma ACTH and cortisol concentrations after the administration of various doses of ACTH1–24 (0.025 μg, 0.125 μg, 0.25 μg, 1 μg, 250 μg) in dexamethasone-suppressed normal volunteers. A logarithmic dose-response relationship between the dose of ACTH administered and plasma cortisol concentration was found. Although there was considerable variability in plasma ACTH concentrations, there was, however, a definite correlation between area under the curve for ACTH and area under the curve for cortisol after the various doses of ACTH.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02189969
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