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  • 1
    ISSN: 1432-5233
    Keywords: Key words Chronic pancreatitis ; Elastase 1 ; Exocrine pancreatic function ; Diabetes mellitus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Reduced exocrine pancreatic function has been observed in a high percentage of patients with type 1 diabetes in the past. There are only few data for type 2 diabetes available and they are contradictory. In this study we investigated exocrine pancreatic function in 105 controls and 114 with type 1 or type 2 diabetes mellitus by means of an indirect test (faecal elastase-1 concentration). This test has good sensitivity and specificity for moderate and severe pancreatic insufficiency as compared to the gold standard. Reduced faecal elastase-1 concentrations were found in 56.7% of type 1 patients, 35% of type 2 patients and 18.1% of the controls. Elastase-1 concentrations did not correlate with alcohol consumption, diabetes duration or diabetes therapy. The data found for type 1 patients correspond to those reported in earlier studies. The results for type 2 diabetics show that exocrine pancreatic function is also impaired in a high percentage in this group of patients. Pathogenic concepts to explain these findings as consequences of diabetes complications or insulin deficiency are still under debate. Observations from autopsies and the data of the controls in this study suggest that chronic pancreatitis might be a common problem. In consequence, diabetes secondary to exocrine disease could be much more frequent than believed so far.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Potato research 27 (1984), S. 297-303 
    ISSN: 1871-4528
    Keywords: starch synthesis ; ADPG-pyrophosphorylase ; heat tolerance ; sink activity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Summary The effect of high tuber temperature (30 °C) on the growth rate and carbohydrate metabolism of tubers was studied with 3 cultivars differing in heat tolerance. Subjecting individual tubers to 30°C for 6 days caused cessation of tuber growth. During this period, non-treated tubers (20°C) on the same plant increased in volume. At 30°C, incorporation of14C-labelled assimilates into the ethanol-insoluble fraction (mainly starch) as well as the starch content was significantly reduced. In contrast, the incorporation of14C-labelled assimilates into the sugar fraction was not affected by high tuber temperature. At 30°C the activity of some of the enzymes involved in starch metabolism was depressed. Varietal differences in responses of tuber growth rate and carbohydrate metabolism to high tuber temperature were insignificant. From these preliminary results it is concluded that high soil temperatures may decrease starch content of potato tubers directly by inhibition of the conversion of sugars into starch.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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