ISSN:
0170-2041
Keywords:
1,2-Diazepinones
;
Pyrazolo[3,4-b]pyridines
;
Acetohydrazides
;
2,4-Diones, 3-arylidene
;
Baldwin rules
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The reaction of 2-cyanoacetohydrazide (1) and 2-(ethoxycarbonyl)acetohydrazide (26) with unsaturated 1,3-diketones leading with moderate yields to 1,2-diazepinones (3, 23, 24) and pyrazolo[3,4-b]pyridines (5, 15, 20, 25) together with the corresponding acetohydrazones have been studied. The reaction course depends on the temperature and the relative reactivity of the carbonyl groups of the starting materials. When one of these carbonyl groups is less reactive (benzoyl or ethoxycarbonyl groups), the reaction does not yield diazepinones but only pyrazolo[3,4-b]pyridines and/or acetohydrazones.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jlac.1990199001158
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