Electronic Resource
Springer
Intensive care medicine
26 (2000), S. 105-108
ISSN:
1432-1238
Keywords:
Key words Glucocorticoid deficiency
;
Adrenal malformation
;
Isolated ACTH deficiency
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract An 18-month-old male infant presented with hypoglycemic coma and clinical signs of bronchopneumonia. He was suspected of suffering from septic shock. The patient progressed to irreversible multiple organ failure before the diagnosis of adrenal crisis was established. Plasma levels of ACTH and cortisol remained undetectable. Renin and aldosterone were normal. An autopsy failed to demonstrate any adrenal gland cortical tissue. Immunohistochemical staining demonstrated the presence of all pituitary hormones except ACTH, establishing the diagnosis of isolated ACTH deficiency. Intensive care clinicians should consider adrenal crisis in non-diabetic children with hypoglycemia and rapid circulatory deterioration.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s001340050021
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