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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    BioMetals 4 (1991), S. 1-6 
    ISSN: 1572-8773
    Keywords: Cell respiration ; Cytochromes ; Ferritin ; Transferrin receptor ; Siderophores
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Summary A concise history of selected aspects of iron metabolism is presented. According to present understanding, the element is known to be required for transport and reduction of O2, for reduction Of CO2, N2 and ribonucleotides, and for other essential cellular processes. The contributions of pioneers in the field, preeminent among them the cell physiologist and biochemist Otto Warburg, are recounted.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Molecular genetics and genomics 213 (1988), S. 487-490 
    ISSN: 1617-4623
    Keywords: pColV ; Aerobactin ; Transposition ; IS1 ; Cointegration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Genes determining the high affinity iron transport system mediated by the siderophore aerobactin are flanked in the enterobacterial plasmid pColV-K30 by inverted repeats of IS1 sequences, suggesting that the aerobactin genes are part of a transposon. To study this possibility, the entire region between the two IS1 sequences was cloned as an 18 kb HindIII-BamHI restriction fragment in pUC8 giving plasmid pMO1. A number of derivatives of pMO1, in which aerobactin genes were tagged with a kanamycin resistance gene, were prepared in order to assess the ability of both IS1s to promote the formation of cointegrates with pCJ105, an F derivative devoid of insertion sequences. Mating-out assays indicated that both flanking IS1s were active in cointegrate formation at detectable frequencies. In some cases, the cointegrates could be resolved, the final result being a transposition-like event for the entire aerobactin system.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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