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  • 1
    Electronic Resource
    Electronic Resource
    Corticosteroid response to stress depends upon increased tryptophan availability (1983)
    Springer
    Psychopharmacology 79 (1983), S. 79-81 
    Details
    ISSN: 1432-2072
    Keywords: Corticosteroid response to stress ; Tryptophan availability ; Amino acids ; 5HT synthesis ; Tryptophan ; Tyrosine ; Valine ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Prior administration of valine to rats has been shown previously to prevent restraint stress-induced increases in brain tryptophan and 5HT turnover. The present study demonstrates that the accompanying attenuation of the corticosteroid response to this stress is substantially reversed by administration of tryptophan with the valine. Tyrosine is not effective in reversing this attenuation, and in fact itself attenuates the corticosteroid response to the stress when given alone. It is concluded that at least part of the corticosteroid response to restraint stress is mediated by an increase in serotonergic activity that is dependent on increased supply of the precursor, tryptophan, and that this can be antagonised by either of two amino acids which compete with tryptophan for access to the brain. Implications for stress-associated human disorders are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00433020
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Pentobarbital sodium and attack behavior in male siamese fighting fish (1980)
    Springer
    Psychopharmacology 69 (1980), S. 207-208 
    Details
    ISSN: 1432-2072
    Keywords: Pentobarbital ; Aggression ; Fish behavior ; Sexual behavior
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract An experiment was undertaken to determine the effects of pentobarbital sodium on intraspecific attack behavior in male Siamese fighting fish in an attempt to extend earlier findings with chlordiazepoxide and secobarbital sodium. Pairs of fish fought while immersed in 20 μg/ml or 40 μg/ml pentobarbital sodium or plain water. The 40 μg/ml group showed significantly less attack (e.g., biting, jaw locking) than either control or low dose groups without producing a change in general arousal. Quasisexual behavior, seen in an earlier chlordiazepoxide study, did not occur in the present study.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00427651
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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