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Naloxone inhibits intermale aggression in isolated mice (1983)

Lynch, W. C. ; Libby, L. ; Johnson, H. F.

Springer

Psychopharmacology 79 (1983), S. 370-371

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ISSN: 1432-2072

Keywords: Aggression ; Opioids ; Naloxone ; Pain ; Mice

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Abstract Aggression and thermal pain thresholds were measured in separate groups of isolated male mice following 0.2–5.0 mg/kg SC injections of the opiate antagonist naloxone. The drug inhibited aggressive behaviors dose-dependently, but had no effect on pain. These results suggest that endogenous opioid systems may be activated during repeated intermale aggressive encounters.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00433421

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