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  • Amebic encephalitis  (1)
  • Atheromatous Material  (1)
  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Acta neuropathologica 51 (1980), S. 85-91 
    ISSN: 1432-0533
    Schlagwort(e): Acanthamoeba ; Amebic encephalitis ; Corticosteroids ; Free-living amebas ; Immunosuppression ; Intracranial mass ; Naegleria
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Clinical and brain biopsy or autopsy findings in six patients with Granulomatous Amebic Encephalitis (GAE) due toAcanthamoeba sp. were characterized by focal neurological symptoms, increased intracranial pressure, and focal neuroradiological findings. Craniotomies were performed because of the diagnostic possibility of a mass lesion such as a brain tumor or abscess. In four patients, frozen sections demonstrated free-living amebas. GAE may present as an acute or subacute intracerebral mass lesion with signs and symptoms of focal brain disease and should be differentiated from viral, bacterial, fungal, and other protozoal encephalitides.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Acta neuropathologica 30 (1974), S. 145-154 
    ISSN: 1432-0533
    Schlagwort(e): Aseptic Meningitis ; Atheromatous Material ; Hypersensitivity ; Electron Microscopy ; Macrophages ; Pia-Arachnoid ; Granuloma
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary 500 mg of sterile pooled human atheromatous material was injected into the cisterna magna of 6 mongrel dogs. Repeated cisternal punctures were done at various intervals until sacrifice from 1 day to 28 days following injection. CSF was obtained for cell count, sugar, protein and analysis in the Technicon 6/60 which measured 14 additional chemical and enzymatic variables. All 6 animals showed a prompt cerebrospinal fluid (CSF) pleocytosis which largely subsided during the first 2 weeks after injection. Increased CSF protein content developed more slowly, but was more prolonged than the pleocytosis. There was a variable decrease in CSF sugar and increase in CSF lactate dehydrogenase, calcium and inorganic phosphorous. Light and electron microscopic studies showed an intense acute inflammatory reaction with marked phagocytosis of the foregin material, probably by arachnoidal cells and moderate edematous changes in the astrocytic processes at the site of injection. During the first 2 weeks after the injection the inflammatory reaction became chronic and the edematous changes in the medulla subsided.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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