ISSN:
1432-2234
Keywords:
Peptide models
;
Amino acids
;
Conformations, stable
;
Proteins
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Summary The stable conformations of N and C protected amino acids of the type: HCONH-CHR-CONH2 of glycine,l-alanine andl-valine have been obtained by fully optimizedab-initio computations with a 3–21G basis set. An original procedure has been devised to extract the side-chain/backbone interaction energy and the backbone and side-chain distortion energies. This enables us to analyze the stabilization/destabilization effects introduced by the side-chain in terms of electrostatic, induction and steric hindrance contributions.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01374587
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