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Cardiovascular effects of paroxetine (1990)

Kuhs, H. ; Rudolf, G. A. E.

Springer

Psychopharmacology 102 (1990), S. 379-382

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ISSN: 1432-2072

Keywords: Paroxetine ; Amitriptyline ; Electrocardiogram ; Blood pressure ; Systolic time intervals ; Plasma drug concentration

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Abstract In a double-blind clinical study, electrocardiogram, blood pressure and systolic time intervals were measured in 40 depressive patients treated with either paroxetine (30 mg/day) or amitriptyline (150 mg/day) for 6 weeks. While amitriptyline significantly increased the heart rate, the QTc interval and the PEP/LVET ratio, paroxetine did not alter any of the cardiovascular parameters measured.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF02244107

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