ISSN:
0935-6304
Schlagwort(e):
Gas chromatography
;
Capillary, fused silica
;
Total particulate matter (TPM) and cigarette smoke
;
Trimethylsilylation with BSTFA
;
Chemometrics and pattern recognition
;
Factor and discriminant analysis
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Chemie und Pharmazie
Notizen:
Complex smoke profiles from fused silica capillary gas chromatography of different cigarette types produce rich information requiring computer and sophisticated statistical analysis to reveal the hidden correlation patterns. In our technique, a Cambridge pad containing total particulate matter (TPM) is extracted with Freon-11 in a micro-Soxhlet apparatus. The condenser is maintained at -15°C. After extraction, Freon-11 is allowed to evaporate under mild conditions. Bis(trimethylsilyl)trifuoroacetamide (BSTFA) is subsequently added to the extract. Trimethylsilylation is completed by maintaining the reaction vessel at 60°C for two hours. A microprocessor-controlled capillary gas chromatograph with an automatic sampler is used to generate profiles. A link to a host computer provides for transmission of profile reports and access to various statistical and graphic packages. Factor and discriminant analyses are applied to gas chromatographic data from TPM extracts because of their ability in data reduction, pattern extraction and ranking the importance of the gas chromatographic peaks. Some preliminary results from these statistical analyses are discussed.
Zusätzliches Material:
7 Ill.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1002/jhrc.1240051202
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