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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Archives of toxicology 38 (1977), S. 239-250 
    ISSN: 1432-0738
    Keywords: Analytical data ; TLC ; Other strong acting analgetics ; Nefopam (Ajan®) ; Nor nefopam ; Nefopam-N-oxid ; GC ; Retention index ; UV spectra ; IR spectra ; Mass spectra ; Quantitative determination ; Extraction ; Metabolism ; Analytische Daten ; DC ; Andere stark wirksame Analgetika ; Nefopam (Ajan®) ; Nor-Nefopam ; Nefopam-N-Oxid ; GC ; Retentionsindizes ; UV-Spektren ; IR-Spektren ; Massenspektren ; Quantitative Bestimmung ; Extraktion ; Metabolismus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung In der Arbeit werden analytische Daten zum Nachweis von Nefopam (Ajan®) und einigen Metaboliten (Nor-Nefopam, Nefopam-N-Oxid) beschrieben. Nähere Einzelheiten s. auch Schlüsselwörter.
    Notes: Summary The article describes analytical properties of nefopam (Ajan®) and some metabolites (nor-nefopam, nefopam-N-oxid). For details see key words.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Archives of toxicology 41 (1978), S. 233-238 
    ISSN: 1432-0738
    Keywords: Analytical data ; 1,5-Benzodiazepine ; Clobazam ; Metabolite ; Nor clobazam ; Tranquilizer ; TLC ; GLC ; UV-spectra ; IR-spectra ; Mass spectra ; Extraction behaviour ; Frisium® ; Analytische Daten ; 1,5-Benzodiazepine ; Clobazam ; Metaboliten ; Nor-Clobazam ; Tranquilizer ; DC ; GLC ; UV-Spektren ; IR-Spektren ; Massenspektren ; Extraktionsverhalten ; Frisium®
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung In der Arbeit werden analytische Daten von Clobazam und seinem Hauptmetaboliten Nor-Clobazam mitgeteilt. Nähere Einzelheiten siehe Schlüsselwörter.
    Notes: Abstract The article describes analytical properties of clobazam and its main metabolite nor-clobazam. For details see key words.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    International journal of legal medicine 114 (2000), S. 83-86 
    ISSN: 1437-1596
    Keywords: Key words Age estimation ; Aspartic acid ; racemisation ; Minimal standards ; Quality control
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Notes: Abstract Estimates of the age of living and dead individuals, obtained in order to answer legal or social questions, require minimum quality standards in order to guarantee data quality. We present an outline strategy (with recommendations) for the attainment of quality assurance in age estimation based on aspartic acid racemisation. The strategy is based on a definition of minimum standards for laboratories, including documentation of procedures, methodology and levels of expertise, and the formulation of guidelines for intralaboratory and interlaboratory quality control.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1437-1596
    Keywords: Key words Age estimation ; Forensic practise ; Demands ; State of the art
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Notes: Abstract Age estimation in cadavers, human remains and living individuals may clarify issues with significant legal and social ramifications for individuals as well as for the community. In such cases methods for estimating age should fulfil the following specific demands: (1) they must have been presented to the scientific community, as a rule by publication in peer-reviewed journals, (2) clear information concerning accuracy of age estimation by the method should be available, (3) the methods need to be sufficiently accurate and (4) in cases of age estimation in living individuals principles of medical ethics and legal regulations have to be considered. We have identified and summarized the methods that essentially fulfil these specific demands. In childhood and adolescence morphological methods based on the radiological examination of dental and skeletal development are to be recommended. In adulthood, the accuracy of most morphological methods is much reduced. Here a biochemical method based on aspartic acid racemization in dentine provides the most accurate estimates of age, followed by special morphological dental and skeletal methods. The choice of method has to take account of the individual circumstances of each case. Most methods require either the consultation of specialised and trained scientists or an adequate calibration by the “user”. Very few attempts have been made to find common standardisation, calibration and evaluation procedures or to develop means of quality assurance for methods of age estimation. Efforts in these directions are necessary to guarantee quality standards and adequate answers to the important legal and social issue of age estimation in forensic medicine.
    Type of Medium: Electronic Resource
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