ISSN:
0570-0833
Keywords:
Allopolarization
;
Ambifunctional anions
;
Substituent effects
;
Anions
;
Chemistry
;
General Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The chemistry of ambifunctional anions is of great importance in organic preparations. Planning of syntheses requires a set of rules correlating structure and selectivity. The concept of allopolarization permits a description of substituent effects on kinetically controlled reactions: the change in selectivity is a function of the change in polarity of the ambifunctional anions. The relative charge density P = lx/ly serves as “polarity index”; X and Y are the potential sites of reaction. An attempt is made to illustrate the utility of this principle by means of examples taken from various classes of compounds.
Additional Material:
4 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/anie.197603211
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