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  • 1
    Electronic Resource
    Electronic Resource
    Der Einfluß von Azetylsalizylsäure und Dipridamol auf die Abstoßung allotransplantierter Hundenieren bei präsensibilisierten Empfängern (1976)
    Springer
    Research in experimental medicine 169 (1976), S. 109-122 
    Details
    ISSN: 1433-8580
    Keywords: Renal transplantation ; Graft rejection ; Platelet thrombi ; Antiaggregating drugs
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effect of antiaggregating agents - acetylsalicyclic acid (ASA) and dipyridamol - on the rejection of allotransplanted canine kidneys in presensitized animals were studied. Blood flow dropped more markedly in the control group than in the group treated with ASA and dipyridamol. 24 hours after transplantation the blood flow in this group was significantly higher than in the control group (p 2,5 %) and in the third group treated with dipyridamol alone. The cellular rejection started earlier and was more pronounced in the control group. Only in this group vascular rejection and microthrombi were demonstrated. Urine output ceased 24 to 60 hours after transplantation. The immunosuppressive, antiphlogistic and platelet antiaggregating effect of the combined ASA and dipyridamol therapy is thought to be responsible for the better results in this group. In this experimental model the combined treatment of ASA and dipyridamol results in a later onset of cellular rejection, in better blood-flow of the kidney and later onset of anuria.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01851172
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Wirkung von Acetylsalicylsäure und einem Pyrido-pyrimidin-Derivat auf die Abstoßung allotransplantierter Nieren im Tierexperiment (1975)
    Springer
    Research in experimental medicine 165 (1975), S. 67-73 
    Details
    ISSN: 1433-8580
    Keywords: Renal transplantation ; Graft rejection ; Platelet thrombi ; Antiaggregating drugs ; Nierentransplantation ; Transplantatabstoßung ; Thrombocytenthromben ; Thrombocytenaggregationshemmende Pharmaka
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Thrombocytenaggregationshemmende Pharmaka — Acetylsalicylsäure und 2-Piperazinyl-4-thiomorpholino-pyrido(3,2-d)-pyrimidin-Sulfattrihydrat—werden in ihrer Wirkung auf Abstoßungsreaktionen bei allotransplantierten Nieren an Hunden untersucht. Klinisch findet sich keine Wirksamkeit der Medikamente, dagegen zeigen interessanterweise die histologischen Befunde bei der Acetylsalicylsäuregruppe eine verminderte Abstoßungsreaktion.
    Notes: Summary The effects of anti-thrombotic drugs—Acetyl-salicylic-acid and 2-Piperazinyl-4-thiomorpholino-pyrido(3,2-d)-pyrimidin-sulfat-trihydrat—on rejection reactions of renal allografts in dogs have been studied. From the clinical point of view no effectiveness of the two drugs can be found, whereas the histological findings do clearly show diminished rejection reactions in the Acetylsalicylic-acid group.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01856451
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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