ISSN:
1439-7609
Keywords:
Key words Hemolytic anemia
;
Systemic lupus erythematosus
;
Antiphospholipid antibody
;
Plasma exchange
;
Molecular markers for coagulation and fibrinolysis
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract We report on a 24-year-old woman with systemic lupus erythematosus and lupus anticoagulant who developed chronic thrombotic microangiopathic hemolytic anemia. The patient responded well to a combination of plasma exchange and anticoagulant therapy. Changes in the molecular markers for coagulation and fibrinolysis corresponded with the disease activity. We suggest that thrombotic microangiopathic hemolytic anemia should be suspected when anemia and thrombocytopenia of unknown etiologies occur in systemic lupus erythematosus. In such cases, the evaluation of molecular markers for coagulation and fibrinolysis might be helpful both for diagnosis and for assessing the response to therapy.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/PL00012174
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