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  • 1
    Electronic Resource
    Electronic Resource
    Elevated triglyceride-rich lipoproteins in diabetes (1996)
    Springer
    Acta diabetologica 33 (1996), S. 205-210 
    Details
    ISSN: 1432-5233
    Keywords: Key words Apolipoprotein B-48 ; Apolipoprotein B-100 ; Triglyceride-rich lipoprotein ; Non-insulin-dependent ; diabetes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The role of the intestine in cholesterol metabolism in human diabetes is unclear, although abnormalities have been demonstrated in cholesterol synthesis and absorption in diabetic animals. This study examines the relationship between fasting and post-prandial apolipoprotein B-48 in type 2 (non-insulin-dependent) diabetic and non-diabetic subjects. Eight type 2 diabetic patients and ten healthy non-diabetic control subjects were given a high-fat meal (1300 kcal), and the triglyceride-rich lipoprotein fraction was isolated by ultracentrifugation (d〈1.006 g/ml) from fasting and post-prandial plasma. Apolipoprotein B-48 and apo B-100 were separated on 4%–15% gradient gels and quantified by densitometric scanning with reference to a purified low-density lipoprotein (LDL) apo B-100 preparation. Diabetic patients had significantly higher concentrations of apo B-48 and apo B-100 in both the fasting (P〈0.05) and post-prandial (P〈0.001) triglyceride-rich lipoprotein samples compared with non-diabetic subjects. The diabetic patients also exhibited a significantly different post-prandial profile for apo B-48 and apo B-100, with a prolonged increase and a later post-prandial peak, than the non-diabetic subjects (P〈0.01). These results suggest that the raised fasting triglyceride-rich lipoproteins, often found in diabetes, are associated with apo B-48 and may be derived from increased intestinal chylomicron production. The post-prandial pattern suggests an abnormality in intestinal production as well as hepatic clearance of apo B-48 in type 2 diabetes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02048544
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Elevated triglyceride-rich lipoproteins in diabetes (1996)
    Springer
    Acta diabetologica 33 (1996), S. 205-210 
    Details
    ISSN: 1432-5233
    Keywords: Apolipoprotein B-48 ; Apolipoprotein B-100 ; Triglyceride-rich lipoprotein ; Non-insulin-dependent diabetes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The role of the intestine in cholesterol metabolism in human diabetes in unclear, although abnormalities have been demonstrated in cholesterol synthesis and absorption in diabetic animals. This study examines the relationship between fasting and post-prandial apolipoprotein B-48 in type 2 (non-insulin-dependent) diabetic and non-diabetic subjects. Eight type 2 diabetic patients and ten healthy non-diabetic control subjects were given a high-fat meal (1300 kcal), and the triglyceride-rich lipoprotein fraction was isolated by ultracentrifugation (d〈1.006 g/ml) from fasting and post-prandial plasma. Apolipoprotein B-48 and apo B-100 were separated on 4%–15% gradient gels and quantified by densitometric scanning with reference to a purified low-density lipoprotein (LDL) apo B-100 preparation. Diabetic patients had significantly higher concentrations of apo B-48 and apo B-100 in both the fasting (P〈0.05) and post-prandial (P〈0.001) triglyceride-rich lipoprotein samples compared with non-diabetic subjects. The diabetic patients also exhibited a significantly different post-prandial profile for apo B-48 and apo B-100, with a prolonged increase and a later post-prandial peak, than the non-diabetic subjects (P〈0.01). These results suggest that the raised fasting triglyceride-rich lipoproteins, often found in diabetes, are associated with apo B-48 and may be derived from increased intestinal chylomicron production. The post-prandial pattern suggests an abnormality in intestinal production as well as hepatic clearance of apo B-48 in type 2 diabetes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02048544
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Heavy metals in Jamaican surface soils (1996)
    Springer
    Environmental geochemistry and health 18 (1996), S. 113-121 
    Details
    ISSN: 1573-2983
    Keywords: Heavy metals ; arsenic ; cadmium ; copper ; lead ; soils ; neutron activation analysis ; X-ray fluorescence atomic absorption spectrophotometry ; bauxite
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Medicine
    Notes: Abstract A regional survey of Jamaican surface soils has been conducted in which more than 200 samples were collected at a sample density of 1 per 64 km2 across the island and analysed for total concentrations of 31 elements by instrumental neutron activation analysis (INAA), energy dispersive X-ray fluorescence (EDXRF) analysis and atomic absorption spectrophotometry (AAS). The aim of the survey was to begin the construction of a high-precision geochemical database to provide information on elemental levels in soils for application to environmental studies, agriculture, and human and animal health. Results on the regional scale are presented for As, Cd, Cu, Hg and Pb. Although Jamaican surface soils are enriched in several heavy metals compared with world soil means and crustal abundances, lead is of particular importance at this stage because of its occurrence in residential areas. Except for Cu, the distribution maps of these elements are highly correlated with bauxite which in Jamaica is associated with white limestone geology and residualterra rossa soils.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01771287
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Suspended particulates in the Jamaican atmosphere (1997)
    Springer
    Environmental geochemistry and health 19 (1997), S. 0-0 
    Details
    ISSN: 1573-2983
    Keywords: Atmospheric particulates ; bromine ; Jamaica ; lead
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Medicine
    Notes: Abstract The results of a survey of air particulates at 23 sites across Jamaica for total suspended particulates (TSP), Al, Br, Cl, Na, Pb, and V, by instrumental neutron activation analysis (INAA) and X-ray fluorescence analysis (XRF) are reported. The geometric mean of TSP values, 35 g m-3, is well within the World Health Organisation's standard of 60 g m-3 for TSP, but in areas of high vehicular traffic density the TSP values exceeded this limit. The correlation coefficient between Br and Pb concentrations in the particulates was 0.92 and the Br/Pb ratio of 0.38 compares well with a ratio of 0.39 found in commercial petrol indicating that the exhaust from vehicular traffic is the major source of Pb in atmospheric particulate matter in Jamaica.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1018481901288
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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