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  • 1
    Electronic Resource
    Electronic Resource
    Climbing behavior induced by apomorphine in mice: a simple test for the study of dopamine receptors in striatum (1976)
    Springer
    Psychopharmacology 50 (1976), S. 1-6 
    Details
    ISSN: 1432-2072
    Keywords: Climbing behavior ; Dopamine receptors ; Apomorphine ; Antipsychotics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Mice treated with low doses of apomorphine tend to adopt a vertical position along the walls of their cage. Optimal conditions have been defined to obtain a reliable dose-response relationship. This peculiar behavior appears to be elicited by stimulation of dopamine receptors in the striatum: it is suppressed after coagulation of this structure while it is facilitated when these receptors are made hypersensitive by previous treatments with 6-hydroxydopamine or haloperidol; on the other hand, it is not modified by coagulation of the nucleus accumbens. The relative efficacy of various agonists and antagonists of dopamine receptors have been determined on this test. It appears that this stereotyped behavior might represent a convenient mean to assess the stimulation of striatal dopamine receptors in mice.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00634146
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    A gradual score to evaluate the climbing behaviour elicited by apomorphine in mice (1978)
    Springer
    Psychopharmacology 56 (1978), S. 233-234 
    Details
    ISSN: 1432-2072
    Keywords: Stereotyped behaviour ; Apomorphine ; Dopamine receptors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Mice treated with apomorphine tend to adopt a vertical position in a stereotyped manner. A quantal evaluation of this behaviour, taking into account its frequency and duration, leads to a biphasic dose-response curve that reveals opposite actions of the dopamine agonist.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00431856
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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