ISSN:
1432-2048
Keywords:
Arabidopsis
;
Calyculin-A
;
Okadaic acid
;
Protein phosphatase
;
Root development
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Abstract Emerging evidence suggests that protein phosphatases play an important role in the growth and development of higher plants. We report here on the effects of okadaic acid and calyculin-A, two specific and potent inhibitors of the type-1 and type-2A families of serine/ threonine protein phosphatases, on the growth and development ofArabidopsis thaliana L. roots. Application of these drugs in nanomolar ranges arrested root hair growth, severely affected the shape of cells within the zone of elongation and inhibited root growth rates. Root hair elongation was inhibited by concentrations of okadaic acid and calyculin-A as low as 3 nM. The pleiotropic effects of okadaic acid and calyculin-A point to multiple functions for type-1 and -2A protein phosphatases in controlling root growth and development.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00714465
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